The supply-chain logistics – storage and transportation over long distances – and downstream processes in biofuel production are adversely impacted by the moisture content in the biomass feedstock. Most woody, herbaceous, low-cost biomass resources such as municipal organic solid wastes and forest residues have moisture content over 30% (of the wet-biomass mass). This makes them less amenable to thermochemical biomass-to-biofuel conversion technologies like pyrolysis and gasification. If pyrolyzed or gasified, the resulting biofuels have a higher moisture content, which truncates their calorific values. During storage, there is a loss of dry matter owing to a tendency to compost aerobically/anaerobically, which is detrimental to the quality of the biomass as a potential source of biofuel. Beyond that, fire hazards due to the spontaneous combustion of wet biomass are not uncommon, necessitating storage in a dry condition. However, drying high-moisture biomass is energy-intensive. The quality of the product and the efficiency of drying are affected by particle sizes and drying technologies adopted. Within this chapter, the authors focus on managing and controlling the moisture content of the biomass utilized in the biofuels sector by resorting to drying and torrefaction technologies. The chapter dwells on drying principles, models and media in drying systems, types of drying systems, mechanical dewatering and torrefaction, the impact of drying, dewatering, and torrefaction on the physical and chemical properties of the end-product, and techno-economic analysis of torrefaction.