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Jakobsson, Niklas, ProfessorORCID iD iconorcid.org/0000-0002-7143-8793
Publications (10 of 74) Show all publications
Bonander, C., Jakobsson, N., Gudmundsdottir, K. K., Svennberg, E. & Engdahl, J. (2025). Atrial fibrillation screening for stroke prevention: an instrumental variables meta-analysis addressing varying participation rates. Europace, 27(2), Article ID euaf030.
Open this publication in new window or tab >>Atrial fibrillation screening for stroke prevention: an instrumental variables meta-analysis addressing varying participation rates
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2025 (English)In: Europace, ISSN 1099-5129, E-ISSN 1532-2092, Vol. 27, no 2, article id euaf030Article in journal (Refereed) Published
Place, publisher, year, edition, pages
Oxford University Press, 2025
Keywords
Atrial fibrillation screening, Mass screening, Randomized controlled trial, Meta-analysis
National Category
Cardiology and Cardiovascular Disease Pharmacology and Toxicology
Research subject
Economics
Identifiers
urn:nbn:se:kau:diva-103959 (URN)10.1093/europace/euaf030 (DOI)001437345700001 ()39953895 (PubMedID)2-s2.0-86000671276 (Scopus ID)
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare, 2020-00962
Available from: 2025-04-11 Created: 2025-04-11 Last updated: 2025-10-16Bibliographically approved
Bonander, C., Hammar, O., Jakobsson, N., Bensch, G., Holzmeister, F. & Brodeur, A. (2025). “Try to Balance the Baseline”: A comment on “Parent–teacher meetings and student outcomes. European Economic Review, 175, Article ID 105021.
Open this publication in new window or tab >>“Try to Balance the Baseline”: A comment on “Parent–teacher meetings and student outcomes
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2025 (English)In: European Economic Review, ISSN 0014-2921, E-ISSN 1873-572X, Vol. 175, article id 105021Article in journal (Refereed) Published
Abstract [en]

Islam (2019) reports results from a cluster randomized field experiment in Bangladesh that examines the effects of parent–teacher meetings on student test scores in primary schools. The reported findings suggest strong positive effects across multiple subjects. In this report, we demonstrate that the school-level randomization cannot have been conducted as the author claims. Specifically, we show that the nine included Bangladeshi unions all have a share of either 0% or 100% treated or control schools. Additionally, we uncover irregularities in baseline scores, which for the same students and subjects vary systematically across the author's data files in ways that are unique to either the treatment or control group. We also discovered data on two unreported outcomes and data collected from the year before the study began. Results using these data cast further doubt on the validity of the original study. Moreover, in a survey asking parents to evaluate the parent–teacher meetings, we find that parents in the control schools were more positive about this intervention than those in the treated schools. We also find undisclosed connections to two additional RCTs.

Keywords
Bangladesh, Field experiments, Reproduction, Student outcomes
National Category
Economics
Research subject
Economics
Identifiers
urn:nbn:se:kau:diva-104329 (URN)10.1016/j.euroecorev.2025.105021 (DOI)001467004700001 ()2-s2.0-105001991384 (Scopus ID)
Available from: 2025-05-12 Created: 2025-05-12 Last updated: 2025-10-16Bibliographically approved
Chrysoulakis, A., Gerell, M. & Jakobsson, N. (2024). A study of security guard deployment and crime reduction in three locations in southern Sweden. Nordic Journal of Criminology, 26(1), 1-8
Open this publication in new window or tab >>A study of security guard deployment and crime reduction in three locations in southern Sweden
2024 (English)In: Nordic Journal of Criminology, ISSN 2578-983X, E-ISSN 2578-9821, Vol. 26, no 1, p. 1-8Article in journal (Refereed) Published
Abstract [en]

This study evaluates the impact of the LOV3 policy—which allows the police to mandate security guards topatrol and maintain order in public environments—on local crime rates in three locations within Malmö andHelsingborg, the two largest cities in southern Sweden, using data from March 2020 to November 2022. We useinterrupted time series analyses on daily crime data to assess the policy’s effects on reported crime rates. Ourfindings, which reveal no significant impact of the LOV3 policy on reported crimes in the examined locations,underscore the need for further research and refinement of crime prevention strategies

Keywords
crime prevention, policy evaluation, regression discontinuity design, differences-in-differences, urban security, Sweden
National Category
Social Sciences Other Social Sciences not elsewhere specified
Research subject
Economics
Identifiers
urn:nbn:se:kau:diva-103279 (URN)10.18261/njc.26.1.1 (DOI)2-s2.0-85218761210 (Scopus ID)
Available from: 2025-02-20 Created: 2025-02-20 Last updated: 2025-12-01Bibliographically approved
Svensson, M., Strand, G. C., Bonander, C., Johansson, N. & Jakobsson, N. (2024). Analyses of quality of life in cancer drug trials - a review of measurements and analytical choices in post-reimbursement studies. BMC Cancer, 24(1), Article ID 311.
Open this publication in new window or tab >>Analyses of quality of life in cancer drug trials - a review of measurements and analytical choices in post-reimbursement studies
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2024 (English)In: BMC Cancer, E-ISSN 1471-2407, Vol. 24, no 1, article id 311Article, review/survey (Refereed) Published
Abstract [en]

Objectives: For drugs reimbursed with limited evidence of patient benefits, confirmatory evidence of overall survival (OS) and quality of life (QoL) benefits is important. For QoL data to serve as valuable input to patients and decision-makers, it must be measured and analyzed using appropriate methods. We aimed to assess the measurement and analyses of post-reimbursement QoL data for cancer drugs introduced in Swedish healthcare with limited evidence at the time of reimbursement. Methods: We reviewed any published post-reimbursement trial data on QoL for cancer drugs reimbursed in Sweden between 2010 and 2020 with limited evidence of improvement in QoL and OS benefits at the time of reimbursement. We extracted information on the instruments used, frequency of measurement, extent of missing data, statistical approaches, and the use of pre-registration and study protocols. Results: Out of 22 drugs satisfying our inclusion criteria, we identified published QoL data for 12 drugs in 22 studies covering multiple cancer types. The most frequently used QoL instruments were EORTC QLQ-C30 and EQ-5D-3/5L. We identified three areas needing improvement in QoL measurement and analysis: (i) motivation for the frequency of measurements, (ii) handling of the substantial missing data problem, and (iii) inclusion and adherence to QoL analyses in clinical trial pre-registration and study protocols. Conclusions: Our review shows that the measurements and analysis of QoL data in our sample of cancer trials covering drugs initially reimbursed without any confirmed QoL or OS evidence have significant room for improvement. The increasing use of QoL assessments must be accompanied by a stricter adherence to best-practice guidelines to provide valuable input to patients and decision-makers. 

Place, publisher, year, edition, pages
BioMed Central (BMC), 2024
Keywords
Cancer, Health-related quality of life, Patient-reported outcomes, Quality assessment, Randomized controlled trials
National Category
Cancer and Oncology Health Care Service and Management, Health Policy and Services and Health Economy Surgery
Research subject
Economics
Identifiers
urn:nbn:se:kau:diva-99184 (URN)10.1186/s12885-024-12045-8 (DOI)001180646300008 ()38448848 (PubMedID)2-s2.0-85186928709 (Scopus ID)
Funder
Jan Wallander and Tom Hedelius Foundation and Tore Browaldh Foundation, P21-0018
Available from: 2024-04-04 Created: 2024-04-04 Last updated: 2025-10-16Bibliographically approved
Pareigis, J., Kvarnström, M., Cefa, B., Bai, J. Y., Zawacki-Richter, O., Uhlin, L., . . . Theilmeier, G. (2024). Open networked learning–a course, a community, an approach. International journal for academic development, 29(2), 169-184
Open this publication in new window or tab >>Open networked learning–a course, a community, an approach
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2024 (English)In: International journal for academic development, ISSN 1360-144X, E-ISSN 1470-1324, Vol. 29, no 2, p. 169-184Article in journal (Refereed) Published
Abstract [en]

Open Networked Learning (ONL) is a collaborative open online course for higher education educators worldwide, focusing on open education, collaborative learning, and course design. The interorganizational course welcomes both institutional and open learners from around 30 nations. Delivered 17 times since 2014 with up to 120 participants in each session, ONL employs problem-based learning to foster digital competencies and strengthen community development. Rooted in the European Framework for Digital Competence of Educators (DigCompEdu), a study involving 48 participants revealed statistically significant, across-the-board competence enhancement post-course, affirming ONL’s efficacy. The article also summarizes our experiences and learnings from participating in and organising the course over the past ten years. 

Place, publisher, year, edition, pages
Routledge, 2024
Keywords
Academic development, community of practice, DigCompEdu, open education, problem-based learning
National Category
Pedagogy
Research subject
Business Administration; Economics
Identifiers
urn:nbn:se:kau:diva-100287 (URN)10.1080/1360144X.2024.2350652 (DOI)001223790700001 ()2-s2.0-85193244532 (Scopus ID)
Note

File changed to published version 250611, nr of downloads ahead-of-print: 116

Available from: 2024-06-18 Created: 2024-06-18 Last updated: 2025-10-16Bibliographically approved
Johansson, N., Jakobsson, N. & Svensson, M. (2024). Place or patient as the driver of regional variation in healthcare spending – Discrepancies by category of care. Social Science and Medicine, 342, Article ID 116571.
Open this publication in new window or tab >>Place or patient as the driver of regional variation in healthcare spending – Discrepancies by category of care
2024 (English)In: Social Science and Medicine, ISSN 0277-9536, E-ISSN 1873-5347, Vol. 342, article id 116571Article in journal (Refereed) Published
Abstract [en]

We study how much regional variation in healthcare spending is driven by place- and patient-specific factors using a random sample of 53,620 regional migrants in Sweden. We find notable differences depending on the category of care, with place-specific factors having a significantly larger impact on specialized outpatient care compared to inpatient and pharmaceutical care. The place effect is estimated to 75% of variation in specialized outpatient care, but 26% or less in variations in inpatient care, and 5% in prescription drug spending. We also find that the empirical estimator has a substantial impact on the estimates of the place-specific effect. The results based on the traditional approach in the literature with two-way fixed effects and event-study models produce much larger estimates of the place-specific effect compared to results based on recently developed heterogeneity-robust models. For total healthcare spending, the traditional two-way fixed effects model estimates a place effect of 78%, while the heterogeneity-robust estimator finds a place effect around 10%. This finding indicates that previous results in this literature, all based on traditional two-way fixed-effects regressions, should be interpreted with care. 

Place, publisher, year, edition, pages
Elsevier, 2024
Keywords
Healthcare spending, Regional variation, Movers, Event study, Two-way fixed effects
National Category
Health Care Service and Management, Health Policy and Services and Health Economy Public Health, Global Health and Social Medicine
Research subject
Economics
Identifiers
urn:nbn:se:kau:diva-98341 (URN)10.1016/j.socscimed.2024.116571 (DOI)001161924700001 ()38215643 (PubMedID)2-s2.0-85182385969 (Scopus ID)
Funder
Swedish Research Council, 02708
Available from: 2024-02-02 Created: 2024-02-02 Last updated: 2025-10-16Bibliographically approved
Ekman, M. & Jakobsson, N. (2024). The impact of earlier pub closing hours on emergency calls to the police during the COVID-19 pandemic in Sweden. Addiction Research and Theory, 32(2), 138-142
Open this publication in new window or tab >>The impact of earlier pub closing hours on emergency calls to the police during the COVID-19 pandemic in Sweden
2024 (English)In: Addiction Research and Theory, ISSN 1606-6359, E-ISSN 1476-7392, Vol. 32, no 2, p. 138-142Article in journal (Refereed) Published
Abstract [en]

On 20 November 2020, the government of Sweden banned on-premise alcohol sales after 10:30 p.m. and then after 8 p.m. on December 24. This study aims to estimate the impact of earlier pub closing hours on emergency calls to the police. We use a quasi-experimental hybrid differences-in-differences design, drawing on data for emergency calls in Sweden. The primary outcome measure is the daily number of emergency calls to the police in Sweden 70 days before the intervention and 70 days after the intervention. The primary control series is the daily number of emergency calls to the police in Sweden during the preceding year, 70 days before the intervention and 70 days after the intervention. We fail to find an effect on daily emergency calls, or nighttime emergency calls to the police, from the restrictions on the sale of alcohol. There is, however, some evidence indicating that weekend emergency calls may have been affected, but that potential effect does not translate into an overall effect. While our study is limited in its focus, it contributes to using a wide range of time windows and a large geographical area (the whole of Sweden) to inform on displacement effects, as well as in considering a broader set of robustness checks. We suggest that our results and future work should be seen in light of our limitations and our contribution, respectively.

Place, publisher, year, edition, pages
Taylor & Francis, 2024
Keywords
Alcohol policy, closing hours, natural experiments, crime
National Category
Economics
Research subject
Business Administration
Identifiers
urn:nbn:se:kau:diva-96104 (URN)10.1080/16066359.2023.2228682 (DOI)001018035000001 ()2-s2.0-85163613229 (Scopus ID)
Available from: 2023-07-13 Created: 2023-07-13 Last updated: 2025-10-16Bibliographically approved
Rahnert, K., Steenkamp, G., Jakobsson, N. & Ontong, J. (2024). The impact of observing lecturer hand motor actions on the learning of cognitive skills in higher education. Acta Psychologica, 249, Article ID 104483.
Open this publication in new window or tab >>The impact of observing lecturer hand motor actions on the learning of cognitive skills in higher education
2024 (English)In: Acta Psychologica, ISSN 0001-6918, E-ISSN 1873-6297, Vol. 249, article id 104483Article in journal (Refereed) Published
Abstract [en]

Class demonstrations where the lecturer’s hand motor actions are observable generally have a positive effect on the learning of motor skills because they trigger an effortless process of embodied simulations. Whether the learning of cognitive skills is likewise affected by such visualisations is yet to be investigated and might depend on the learning content as well as other factors. This study aimed to investigate whether showing the lecturer’s hand via a document camera during an introductory financial accounting class affects student learning (transfer performance), cognitive load responses, and note-taking behaviour compared to a writing pad where the lecturer’s hand is not visible. The study utilised a quasi-experimental design in an in-person setting, with a pre-test and post-test comparison of two groups of participants: one group that viewed a lecture video without the lecturer’s hand being visible (n = 509), and another group that viewed the same lecture with the lecturer’s hand being visible (n = 571). The results showed that the with-hand group had a significantly higher increase in test scores compared to the without-hand group. However, the visibility of the hand did not significantly impact cognitive load or note-taking behaviour. The findings have important practical implications for education, as incorporating non-verbal cues such as the lecturer’s hand may effectively enhance learning cognitive skills.

Place, publisher, year, edition, pages
Elsevier, 2024
Keywords
Instructional design, Technology, Observing, Imitating, Note-taking, Hand motor actions
National Category
Educational Sciences
Research subject
Business Administration; Economics
Identifiers
urn:nbn:se:kau:diva-101536 (URN)10.1016/j.actpsy.2024.104483 (DOI)001306788200001 ()2-s2.0-85202960853 (Scopus ID)
Available from: 2024-09-04 Created: 2024-09-04 Last updated: 2025-10-16Bibliographically approved
Jakobsson, N. & Vikström, C. (Eds.). (2023). Bidrag från universitetspedagogisk konferens 2022. Karlstad: Karlstads universitet
Open this publication in new window or tab >>Bidrag från universitetspedagogisk konferens 2022
2023 (Swedish)Collection (editor) (Other academic)
Abstract [sv]

I föreliggande rapport kan du ta del av sju olika utvecklingsprojekt inom undervisning och examination vid Karlstads universitet. Samtliga bidrag i rapporten har utvecklats från projekt som presenterats vid enhetens universitetspedagogiska konferens.

I årets upplaga kan du bland annat läsa om en ny typ av tentamen, en klimatutmaning. Vad händer när studenter uppmanas att under en månads tid göra något annorlunda i sin vardag, så som att resa med cykel eller buss istället för bil? I en annan studie undersöker författarna huruvida det är någon skillnad för studenterna om läraren använder läsplatta eller dokumentkamera i inspelade föreläsningar.

Du får även en inblick i hur flexibla nätbaserade kurser för yrkesverksamma, i samverkan med företag och organisationer, kan bidra till det livslånga lärandet, och inte minst vilken roll sociala medier kan få när en kurs om vetenskaplig metod plötsligt ställs om till distans i pandemitider. 

Publicerade texter i rapportserien kan ligga till grund för pedagogisk meritering vid ansökan om att bli meriterad eller excellent inom undervisning och examination vid Karlstads universitet.

Place, publisher, year, edition, pages
Karlstad: Karlstads universitet, 2023. p. 107
Series
Utveckling av undervisning och examination i högre utbildning: utgiven av Universitetspedagogiska enheten vid Karlstads universitet ; 2023:1
National Category
Educational Sciences
Identifiers
urn:nbn:se:kau:diva-96765 (URN)978-91-7867-404-6 (ISBN)978-91-7867-405-3 (ISBN)
Available from: 2023-09-19 Created: 2023-09-19 Last updated: 2025-10-16Bibliographically approved
Chauca Strand, G., Johansson, N., Jakobsson, N., Bonander, C. & Svensson, M. (2023). Cancer Drugs Reimbursed with Limited Evidence on Overall Survival and Quality of Life: Do Follow-Up Studies Confirm Patient Benefits?. Clinical drug investigation, 43(8), 621-633
Open this publication in new window or tab >>Cancer Drugs Reimbursed with Limited Evidence on Overall Survival and Quality of Life: Do Follow-Up Studies Confirm Patient Benefits?
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2023 (English)In: Clinical drug investigation, ISSN 1173-2563, E-ISSN 1179-1918, Vol. 43, no 8, p. 621-633Article in journal (Refereed) Published
Abstract [en]

Background and ObjectiveCancer drug costs have increased considerably within healthcare systems, but many drugs lack quality-of-life (QoL) and overall survival (OS) data at the time of reimbursement approval. This study aimed to review the extent of subsequent literature documenting improvements in OS and QoL for cancer drug indications where no such evidence existed at the time of reimbursement approval.MethodsDrug indications with claims of added therapeutical value but a lack of evidence on OS and QoL that were reimbursed between 2010 and 2020 in Sweden were included for review. Searches were conducted in PubMed and ClinicalTrial.gov for randomized controlled trials examining OS and QoL.ResultsOf the 22 included drug indications, seven were found to have at least one trial with conclusive evidence of improvements in OS or QoL after a mean follow-up of 6.6 years. The remaining 15 drug indications either lacked subsequent randomized controlled trial data on OS or QoL (n = 6) or showed no statistically significant improvements (n = 9). Only one drug demonstrated evidence of improvement in both OS and QoL for its indication.ConclusionsA considerable share of reimbursed cancer drug indications continue to lack evidence of improvement in both OS and QoL. With limited healthcare resources and an increasing cancer burden, third-party payers have strong incentives to require additional post-reimbursement data to confirm any improvements in OS and QoL.

Place, publisher, year, edition, pages
Springer, 2023
Keywords
renal-cell carcinoma, european medicines agency, early breast-cancer, clinical benefit, lung-cancer, phase-III, end-points, open-label, everolimus, outcomes
National Category
Cancer and Oncology Health Care Service and Management, Health Policy and Services and Health Economy
Research subject
Economics
Identifiers
urn:nbn:se:kau:diva-96400 (URN)10.1007/s40261-023-01285-4 (DOI)001039851200001 ()37505421 (PubMedID)2-s2.0-85169757424 (Scopus ID)
Funder
The Jan Wallander and Tom Hedelius Foundation, P21-0018University of Gothenburg
Available from: 2023-08-17 Created: 2023-08-17 Last updated: 2025-10-16Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-7143-8793

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