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  • 51.
    Johansson, N.
    et al.
    Health Metrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för ekonomi, kommunikation och IT, Avdelningen för nationalekonomi och statistik. Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013). Norwegian Social Res NOVA, Oslo, Norway.
    Svensson, Mikael
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013). Karlstads universitet, Fakulteten för ekonomi, kommunikation och IT, Avdelningen för nationalekonomi och statistik. Williams Coll, Dept Econ, Williamstown, MA 01267 USA.
    Regional variation in health care utilization in Sweden: The importance of demand-side factors2018Ingår i: BMC Health Services Research, E-ISSN 1472-6963, Vol. 18, nr 1, artikel-id 403Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Differences in health care utilization across geographical areas are well documented within several countries. If the variation across areas cannot be explained by differences in medical need, it can be a sign of inefficiency or misallocation of public health care resources. Methods: In this observational, longitudinal panel study we use regional level data covering the 21 Swedish regions (county councils) over 13 years and a random effects model to assess to what degree regional variation in outpatient physician visits is explained by observed demand factors such as health, demography and socio-economic factors. Results: The results show that regional mortality, as a proxy for population health, and demography do not explain regional variation in visits to primary care physicians, but explain about 50% of regional variation in visits to outpatient specialists. Adjusting for socio-economic and basic supply-side factors explains 33% of the regional variation in primary physician visits, but adds nothing to explaining the variation in specialist visits. Conclusion: 50-67% of regional variation remains unexplained by a large number of observable regional characteristics, indicating that omitted and possibly unobserved factors contribute substantially to the regional variation. We conclude that variations in health care utilization across regions is not very well explained by underlying medical need and demand, measured by mortality, demographic and socio-economic factors.

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  • 52.
    Johansson, Naimi
    et al.
    University Gothenburg, Sweden.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013). Norway.
    Svensson, Mikael
    Gothenburg University, Sweden.
    Effects of primary care cost-sharing among young adults: Varying impact across income groups and gender2019Ingår i: European Journal of Health Economics, ISSN 1618-7598, E-ISSN 1618-7601, Vol. 20, nr 8, s. 1271-1280Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    We estimate the price sensitivity in health care among adolescents and young adults, and assess how it varies across income groups and gender, using a regression discontinuity design. We use the age differential cost-sharing in Swedish primary care as our identification strategy. At the 20th birthday, the copayment increases from €0 to approx. €10 per primary care physician visit and close to this threshold the copayment faced by each person is distributed almost as good as if randomized. The analysis is performed using high-quality health care and economic register data of 73,000 individuals aged 18–22. Our results show that the copayment decreases the average number of visits by 7%. Among women visits are reduced by 9%, for low-income individuals by 11%, and for low-income women by 14%. In conclusion, modest copayments have significant utilization effects, and even in a policy context with relatively low income inequalities, the effect is substantially larger in low-income groups and among women.

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  • 53.
    Johansson, Naimi
    et al.
    Örebro University, Sweden; University of Gothenburg, Sweden.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Svensson, Mikael
    University of Gothenburg, Sweden; University of Florida, United States.
    Place or patient as the driver of regional variation in healthcare spending – Discrepancies by category of care2024Ingår i: Social Science and Medicine, ISSN 0277-9536, E-ISSN 1873-5347, Vol. 342, artikel-id 116571Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    We study how much regional variation in healthcare spending is driven by place- and patient-specific factors using a random sample of 53,620 regional migrants in Sweden. We find notable differences depending on the category of care, with place-specific factors having a significantly larger impact on specialized outpatient care compared to inpatient and pharmaceutical care. The place effect is estimated to 75% of variation in specialized outpatient care, but 26% or less in variations in inpatient care, and 5% in prescription drug spending. We also find that the empirical estimator has a substantial impact on the estimates of the place-specific effect. The results based on the traditional approach in the literature with two-way fixed effects and event-study models produce much larger estimates of the place-specific effect compared to results based on recently developed heterogeneity-robust models. For total healthcare spending, the traditional two-way fixed effects model estimates a place effect of 78%, while the heterogeneity-robust estimator finds a place effect around 10%. This finding indicates that previous results in this literature, all based on traditional two-way fixed-effects regressions, should be interpreted with care. 

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  • 54.
    Jonsson, Sofia
    et al.
    Univ Gothenburg, Dept Polit Sci, Gothenburg, Sweden..
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Is buying sex morally wrong?: Comparing attitudes toward prostitution using individual-level data across eight Western European countries2017Ingår i: Women's Studies: International Forum, ISSN 0277-5395, E-ISSN 1879-243X, Vol. 61, s. 58-69Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    States try to combat sex trafficking through both the criminalization of buying sex and by entirely legalizing or regulating the market for prostitution. Proponents of criminalization argue that this approach leads to less acceptance of prostitution, creating a smaller sex market, and reducing the inflow of trafficked victims. Few studies examine if prostitution laws are associated with attitudes toward prostitution. We assess attitudes in eight European countries, using newly collected survey data. This is one of few studies comparing attitudes across different prostitution regimes. Citizens in countries where the purchase of sex is criminalized are less tolerant toward the buying of sex compared to citizens living in countries where the purchase of sex is legalized. Also, people viewing gender equality as important are less accepting of the purchase in countries where buying sex is prohibited, but more accepting in countries where buying sex and running a brothel are legal. (C) 2017 Elsevier Ltd. All rights reserved.

  • 55. Kotsadam, Andreas
    et al.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för ekonomi, kommunikation och IT, Avdelningen för nationalekonomi och statistik.
    Do laws affect attitudes?: An assessment of the Norwegian Prostitution Law using Longitudinal Data2011Ingår i: International Review of Law and Economics, ISSN 0144-8188, E-ISSN 1873-6394, Vol. 31, nr 2, s. 103-115Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The question of whether laws affect attitudes has inspired scholars across many disciplines, but empirical knowledge is sparse. Using longitudinal survey data from Norway and Sweden, collected before and after the implementation of a Norwegian law criminalizing the purchase of sexual services, we assess the short-run effects on attitudes using a difference-in-differences approach. In the general population, the law did not affect moral attitudes toward prostitution. However, in the Norwegian capital, where prostitution was more visible before the reform, the law made people more negative toward buying sex. This supports the claim that proximity and visibility are important factors for the internalization of legal norms.

  • 56.
    Kotsadam, Andreas
    et al.
    University of Oslo.
    Jakobsson, Niklas
    Norwgian social research.
    Shame on you, John! Laws, stigmatization, and the demand for sex2014Ingår i: European Journal of Law and Economics, ISSN 0929-1261, E-ISSN 1572-9990, Vol. 37, nr 3, s. 393-404Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The present article contributes to the literature on prostitution by shedding light on the effects of the criminalization of buying sex on the amount of prostitution bought, as well as on the proposed theoretical mechanisms underlying this change. We find indications that criminalizing the buying of sex may decrease the quantity of sex bought. While we find that stigma influences the demand for sex, we do not find that stigma increases as a result of the law. Therefore, the possible reduced quantity of sex bought is probably due to the more direct risk of getting caught.

  • 57.
    Kotsadam, Andreas
    et al.
    Olso universitet.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för ekonomi, kommunikation och IT, Avdelningen för nationalekonomi och statistik.
    Uformell eldreomsorg: et hinder for kvinner på arbetsmarkedet?2012Ingår i: Søkelys på arbeidsmarkedet, ISSN 0800-6199, E-ISSN 1504-7970, Vol. 29, nr 1-2, s. 97-110Artikel i tidskrift (Refereegranskat)
  • 58.
    Modig, Niclas
    et al.
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Institutionen för samhälls- och kulturvetenskap (from 2013).
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Are they ready for teaching?: A study of pre-service teachers’ confidence in the field of economicsManuskript (preprint) (Övrigt vetenskapligt)
  • 59.
    Næss, Siri
    et al.
    HIOA, Norwegian Social Res NOVA, Oslo, Norway.
    Blekesaune, Morten
    Univ Agder, Kristiansand, Norway.
    Jakobsson, Niklas
    HIOA, Norwegian Social Res NOVA, Oslo, Norway.
    Marital transitions and life satisfaction: Evidence from longitudinal data from Norway2015Ingår i: Acta Sociologica, ISSN 0001-6993, E-ISSN 1502-3869, Vol. 58, nr 1, s. 63-78Artikel i tidskrift (Refereegranskat)
  • 60.
    Oien, Henning
    et al.
    Oslo Metropolitan University, Oslo.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Bonander, Carl
    Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Institutionen för miljö- och livsvetenskaper (from 2013).
    The impact of community-based interventions for the older population: a quasi-experimental study of a hip-fracture prevention program in Norway2018Ingår i: BMC Geriatrics, ISSN 1471-2318, E-ISSN 1471-2318, Vol. 18, nr 1, artikel-id 311Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BackgroundHip fractures among older adults are a major public health problem in many countries. Hip fractures are associated with expensive health care treatments, and serious adverse effects on patients' health and quality-of-life. In this paper, we estimate the effect of a community-based hip fracture prevention program that was initiated in 16 Norwegian municipalities in 2007. Specifically, the participating municipalities implemented one or more of the following interventions: exercise programs for older adults, information and education campaigns to communicate how to effectively reduce falls to care workers and older adults, and preventive home safety assessment and modification help services.MethodsWe used a difference-in-difference design, and identified control municipalities by matching on pre-intervention trends in the outcome. The outcome measure was the incidence of hip-fractures among older adults (65years).ResultsWe found no statistically significant effects of the implemented program on the incidence of hip fractures, on average, in older subgroups (80years) or in municipality-specific analyses.ConclusionsIt is unclear whether the interventions managed to achieve a change in hip fracture rates at the population level.

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  • 61.
    Pareigis, Jörg
    et al.
    Karlstads universitet.
    Kvarnström, M.
    Linköping University, Sweden.
    Cefa, B.
    University of Oldenburg, Germany.
    Bai, J. Y. H.
    University of Oldenburg, Germany.
    Zawacki-Richter, O.
    University of Oldenburg, Germany.
    Uhlin, L.
    Linköping University, Sweden.
    Jakobsson, Niklas
    Karlstads universitet.
    Theilmeier, G.
    University of Oldenburg, Germany.
    Open networked learning–a course, a community, an approach2024Ingår i: International journal for academic development, ISSN 1360-144X, E-ISSN 1470-1324Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Open Networked Learning (ONL) is a collaborative open online course for higher education educators worldwide, focusing on open education, collaborative learning, and course design. The interorganizational course welcomes both institutional and open learners from around 30 nations. Delivered 17 times since 2014 with up to 120 participants in each session, ONL employs problem-based learning to foster digital competencies and strengthen community development. Rooted in the European Framework for Digital Competence of Educators (DigCompEdu), a study involving 48 participants revealed statistically significant, across-the-board competence enhancement post-course, affirming ONL’s efficacy. The article also summarizes our experiences and learnings from participating in and organising the course over the past ten years. 

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  • 62.
    Rahnert, Katharina
    et al.
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för ekonomi, kommunikation och IT (nedlagd), Avdelningen för nationalekonomi och statistik. Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Dokumentkamera eller skrivplatta 2.0: Har valet av presentationsverktyg betydelse för studenters lärande?2023Ingår i: Bidrag från universitetspedagogisk konferens 2022 / [ed] Jakobsson, Niklas; Vikström, Carina, Karlstad: Karlstads universitet, 2023, s. 39-48Kapitel i bok, del av antologi (Refereegranskat)
    Abstract [sv]

    I en tidigare studie (Rahnert, 2022a) har distansundervisningens utmaningar med att presentera exempel eller övningar på elektroniska motsvarigheter till en whiteboardtavla belysts. I två synkrona redovisningskurser undersöktes om studenters upplevda lärande underlättas när bokföringsövningar presenteras med hjälp av en dokumentkamera som synliggör lärarens hand och det läraren skriver, eller en skrivplatta som enbart synliggör det läraren skriver. Studien visade att dokumentkameran underlättar studenters upplevda lärande avsevärt mer än skrivplattan.Denna studie bygger vidare på den tidigare genom att undersöka huruvida val av presentationsverktyg har betydelse för redovisningsstudenters faktiska lärande. I ett experiment fick slumpmässigt valda studenter i en kurs i grundläggande redovisning antingen se en övning som presenterades med hjälp av en dokumentkamera (lärarens hand synlig) eller en skrivplatta (lärarens hand inte synlig). Studenters lärande mättes med hjälp av tester före och efter övningen (pre- och post-tester). Resultaten visar att den genomsnittliga andelen korrekta svar ökade något mer från pre- till post-testerna för de studenter som hade sett övningen som presenterades med hjälp av dokumentkameran. Dock var skillnaderna mellan grupperna inte statistiskt signifikanta, varför försiktighet med att argumentera för dokumentkameran bör iakttas.

  • 63.
    Ryen, Linda
    et al.
    Swedish Civil Contingencies Agency .
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Svensson, Mikael
    University of Gothenburg.
    What should guide priority setting in health care?: A study of public preferences in Sweden2019Ingår i: Nordic Journal of Health Economics, ISSN 1892-9729, E-ISSN 1892-9710, Vol. 7, nr 1, s. 82-89Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Priority setting criteria in health care are commonly set by politicians on behalf of the public. It is desirable that these criteria are in line with societal preferences in order to gain acceptance for decisions on what health services to provide and reimburse. We study public preferences for the allocation of the health care budget based on age, disease severity and treatment cost. We use data from a web survey where 1,160 respondents provided their views on priority setting criteria in health care. The data was analyzed using multinomial logistic regression analyses and one-sample proportion tests. Between 13 to 25 percent of the respondents agree that age, disease severity and treatment cost are valid criteria for priority setting, whereas 56 to 80 percent support weaker versions of the statements. We also find significant differences within the population; young men are for example more prone to support explicit priority setting criteria. Our results imply a need for trade-offs in health care priority setting if balancing differing preferences among population groups. To achieve a greater understanding for priority setting in general, and for using economic reasoning in particular, there may be a need for more public transparency to make clear that priority setting is inevitable.

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  • 64.
    Störe, Siri Jakobsson
    et al.
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Institutionen för sociala och psykologiska studier (from 2013).
    Beckman, Linda
    Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Institutionen för hälsovetenskaper (from 2013).
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    The effect of robot interventions on sleep in adults: a systematic review and network meta-analysis2022Ingår i: Journal of Clinical Sleep Medicine (JCSM), ISSN 1550-9389, E-ISSN 1550-9397, Vol. 18, nr 7, s. 1877-1884Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Study Objectives: Robotic pets or companion robots have demonstrated positive effects on several emotional and physiological factors in humans. Robots could constitute a complementary or alternative method to treat sleep problems, but individual studies on robots' effectiveness regarding sleep show mixed results. The aim of the current study was to compare the effects of robots, plush toys, and treatment as usual on sleep in adults. Methods: The current study is a systematic review and frequentist network meta-analysis of all randomized and cluster randomized controlled trials comparing the effects of robots, plush toys, and treatment as usual on total sleep time in adults. Results: Four studies were included in the analysis. Three studies were considered to have a high risk of bias, whereas one was rated with some concerns. The studies comprised 381 participants. These participants were older adults, with or without dementia, living in nursing homes. The total sleep time was the only common sleep measure included in all 4 studies. The network meta-analysis showed no statistically significant differences between the 3 experimental groups. Conclusions: The robot interventions were not found to have positive effects on total sleep time in older adults compared with plush toys or treatment as usual. Future studies should use robots especially made to target sleep, include a thorough screening of the participants, and exclude people with adequate sleep, select appropriate sleep measures, and report the results appropriately for future meta-analyses.

  • 65.
    Störe, Siri Jakobsson
    et al.
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Institutionen för sociala och psykologiska studier (from 2013).
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    The Effect of Mandala Coloring on State Anxiety: A Systematic Review and Meta-Analysis2022Ingår i: Art Therapy, ISSN 0742-1656, E-ISSN 2159-9394, Vol. 39, nr 4, s. 173-181Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This meta-analysis assessed the effectiveness of mandala coloring, compared with free drawing on state anxiety in adults. A systematic search for studies yielded eight studies, which constituted a total of 578 participants, with 289 in the mandala coloring group and 289 in the free drawing group. The results indicated that coloring mandala designs was not found to reduce state anxiety significantly more than free drawing. Larger effect sizes were found in the studies with lower precision, indicating some evidence of bias toward finding an effect. The findings suggest that mandala coloring and free drawing are equally effective coloring techniques to achieve anxiety reduction. More high-quality studies are warranted before any recommendations can be made with confidence.

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  • 66.
    Störe, Siri Jakobsson
    et al.
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Institutionen för sociala och psykologiska studier (from 2013).
    Norell-Clarke, Annika
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Institutionen för sociala och psykologiska studier (from 2013). Kristianstad University; Örebro University.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Sleep researchers' rankings of sleep journals2023Ingår i: Journal of Sleep Research, ISSN 0962-1105, E-ISSN 1365-2869, Vol. 32, nr 3, artikel-id e13756Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The impact factor is used to rank the quality of scientific journals but has been criticised for a number of reasons. The aim of the study was to investigate sleep researchers' perceptions of sleep journals to determine whether subjective rankings of journals were in line with the journals' impact factors. Clarivate's Journal Citation Reports website was used to identify journals containing the words 'sleep' or 'dream' in the titles with an impact factor since 2018, resulting in 12 journals. A survey including questions about how the respondent would rank these journals (e.g., three most prestigious journals) was developed. A total of 122 sleep researchers completed the survey. Sleep, Sleep Medicine Reviews and Journal of Sleep Research were ranked as the three most prestigious sleep journals, in line with the impact factors of the journals. For the rest of the journals, the subjective rankings and impact factors did not correspond as much.

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  • 67.
    Sund, Björn
    et al.
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013). Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Centrum för personsäkerhet (from 2013).
    Bonander, Carl
    Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Centrum för personsäkerhet (from 2013). Göteborgs universitet.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Jaldell, Henrik
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Do home fire and safety checks by on-duty firefighters decrease the number of fires?: Quasi-experimental evidence from Southern Sweden2019Ingår i: Journal of Safety Research, ISSN 0022-4375, E-ISSN 1879-1247, Vol. 70, s. 39-47Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Introduction: Fire and rescue services Syd, in the south of Sweden, started to conduct home fire and safety checks on a large scale in 2010. The goal was to reduce the damages from residential fires. Method: We estimate the effects of the intervention on the incidence of residential fires and evaluate its economic effect. We use a difference-in-kinks design to analyze time-varying intervention effects and conduct a cost–benefit analysis for the economic evaluation. Results: The results demonstrate that fires and developed fires decrease by a maximum of approximately 6% and 8% per year (assuming 100% causality)and that the intervention has positive economic effects, with the benefits estimated to be maximum 8–11 times higher than the costs. Practical applications: The results should be valuable as input when deciding whether to implement home fire and safety checks elsewhere.

  • 68.
    Svensson, M.
    et al.
    University of Florida, USA.
    Strand, G. Chauca
    University of Gothenburg, Sweden.
    Bonander, Carl
    University of Gothenburg, Sweden.
    Johansson, N.
    University of Gothenburg, Sweden.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Measurement and Analysis of Health-Related Quality of Life Data in Cancer Drug Trials: A Review of Post-Reimbursement Data2023Ingår i: Value in Health, ISSN 1098-3015, E-ISSN 1524-4733, Vol. 26, nr 6, artikel-id S353Artikel i tidskrift (Övrigt vetenskapligt)
  • 69.
    Svensson, Mikael
    et al.
    University of Florida, USA; University of Gothenburg, Sweden.
    Strand, Gabriella Chauca
    University of Gothenburg, Sweden.
    Bonander, Carl
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Centrum för forskning om samhällsrisker, CSR (från 2020). University of Gothenburg, Sweden.
    Johansson, Naimi
    Orebro University, Sweden.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Analyses of quality of life in cancer drug trials - a review of measurements and analytical choices in post-reimbursement studies2024Ingår i: BMC Cancer, E-ISSN 1471-2407, Vol. 24, nr 1, artikel-id 311Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Objectives: For drugs reimbursed with limited evidence of patient benefits, confirmatory evidence of overall survival (OS) and quality of life (QoL) benefits is important. For QoL data to serve as valuable input to patients and decision-makers, it must be measured and analyzed using appropriate methods. We aimed to assess the measurement and analyses of post-reimbursement QoL data for cancer drugs introduced in Swedish healthcare with limited evidence at the time of reimbursement. Methods: We reviewed any published post-reimbursement trial data on QoL for cancer drugs reimbursed in Sweden between 2010 and 2020 with limited evidence of improvement in QoL and OS benefits at the time of reimbursement. We extracted information on the instruments used, frequency of measurement, extent of missing data, statistical approaches, and the use of pre-registration and study protocols. Results: Out of 22 drugs satisfying our inclusion criteria, we identified published QoL data for 12 drugs in 22 studies covering multiple cancer types. The most frequently used QoL instruments were EORTC QLQ-C30 and EQ-5D-3/5L. We identified three areas needing improvement in QoL measurement and analysis: (i) motivation for the frequency of measurements, (ii) handling of the substantial missing data problem, and (iii) inclusion and adherence to QoL analyses in clinical trial pre-registration and study protocols. Conclusions: Our review shows that the measurements and analysis of QoL data in our sample of cancer trials covering drugs initially reimbursed without any confirmed QoL or OS evidence have significant room for improvement. The increasing use of QoL assessments must be accompanied by a stricter adherence to best-practice guidelines to provide valuable input to patients and decision-makers. 

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  • 70.
    Syse, Astri
    et al.
    Statistisk sentralbyrå, Norge.
    Øien, Henning
    Universitetet i Oslo, Högskolan i Oslo, Norge.
    Bugge Solheim, Mari
    Högskolan i Oslo.
    Jakobsson, Niklas
    Karlstads universitet, Fakulteten för humaniora och samhällsvetenskap (from 2013), Handelshögskolan (from 2013).
    Variasjoner i kommunale tildelingsvurderinger av helse- og omsorgstjenester til eldre2015Ingår i: Tidsskrift for velferdsforskning, ISSN 0809-2052, E-ISSN 2464-3076, Vol. 18, nr 3, s. 211-233Artikel i tidskrift (Refereegranskat)
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