Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Sample treatment based on extraction techniques in biological matrices
Najd Consulting Hosp, Riyadh, Saudi Arabia..
Karlstad University, Faculty of Technology and Science, Department of Chemistry and Biomedical Sciences. AstraZeneca R&D Sodertalje, Clin Pharmacol, SE-15185 Sodertalje, Sweden.;AstraZeneca R&D Sodertalje, DMPK, SE-15185 Sodertalje, Sweden.;Karlstad Univ, Dept Chem & Biomed Sci, SE-65188 Karlstad, Sweden.;Stockholm Univ, Dept Analyt Chem, SE-10691 Stockholm, Sweden..ORCID iD: 0000-0002-3862-8878
2011 (English)In: Bioanalysis, ISSN 1757-6180, E-ISSN 1757-6199, Vol. 3, no 17, p. 2003-2018Article, review/survey (Refereed) Published
Resource type
Text
Abstract [en]

The importance of sample preparation methods as the first stage in bioanalysis is described. In this article, the sample preparation concept and strategies will be discussed, along with the requirements for good sample preparation. The most widely used sample preparation methods in the pharmaceutical industry are presented; for example, the need for same-day rotation of results from large numbers of biological samples in pharmaceutical industry makes high throughput bioanalysis more essential. In this article, high-throughput sample preparation techniques are presented; examples are given of the extraction and concentration of analytes from biological matrices, including protein precipitation, solid-phase extraction, liquid-liquid extraction and microextraction-related techniques. Finally, the potential role of selective extraction methods, including molecular imprinted phases, is considered.

Place, publisher, year, edition, pages
2011. Vol. 3, no 17, p. 2003-2018
National Category
Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
Research subject
Biomedical Sciences
Identifiers
URN: urn:nbn:se:kau:diva-40607DOI: 10.4155/BIO.11.201ISI: 000295210300017PubMedID: 21899508OAI: oai:DiVA.org:kau-40607DiVA, id: diva2:905478
Available from: 2016-02-22 Created: 2016-02-22 Last updated: 2017-11-30Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Authority records BETA

Abdel-Rehim, Mohamed

Search in DiVA

By author/editor
Abdel-Rehim, Mohamed
By organisation
Department of Chemistry and Biomedical Sciences
In the same journal
Bioanalysis
Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 66 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf