Aim   To develop and validate a questionnaire for detecting atopic dermatitis in infants and small children from the age of 2months.   Methods  Parents to 60 children answered a written questionnaire prior to a physical examination and individual semistructured interview. Qualitative and quantitative analyses of validity, sensitivity, specificity, and predictive values of the questionnaire were performed.  Results. A total of 27 girls and 33 boys, aged 2 to 71 months, 35 with and 25 without physician-diagnosed eczema, participated. Validation of the questionnaire by comparisons with physicians’ diagnoses showed a sensitivity of 0.91 (95% CI0.77–0.98) and a specificity of 1 (95% CI 0.86–1).  Conclusions. Three questions in a parental questionnaire were sufficient for diagnosing eczema in infants and small children.