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The Importance of Remission in the Treatment of Patients with Schizophrenia Spectrum Syndromes: Clinical Long-term Investigation of Psychosis in Sweden
Karlstad University, Faculty of Economic Sciences, Communication and IT, Department of Psychology.
2009 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The goal of this thesis was to investigate the hypothesis whether symptomatic remission for patents with schizophrenia spectrum syndrome would provide practical and qualitative benefits for patients and for society.

The first work (Paper I) examines the relationship between cross-sectional remission and the patients’ practical resources. The patients’ adaptations to society as well as their employments, living situations and social networks were studied. Their activity of daily living resources are described in terms of the extent to which they could pursue various undertakings autonomously. Their need for care was also studied. The results showed that the patient group that had achieved remission scored better on all of the variables studied, had better resources and less need for medical care and sheltered housing.

The second work (Paper II) analysed the relationship between cross-sectional remission and quality of life, burden placed on patients by the illness, and the patients’ satisfaction with care received and with their medication, and also their capacity for understanding their symptoms and their illness. Even the results of this study showed that the patients in the remission group had a better quality of life, bore a lesser burden, were more satisfied with their care and had better insight into their illness.

The third work (Paper III) studied the patients’ neurocognitive capacity to see if a higher capacity resulted in a higher percentage of patients achieving remission. The results showed unequivocally that the patients in remission consistently performed better in the cognitive tests. They also showed that they even had a larger vocabulary indicating a higher premorbid capacity.

The fourth work (Paper IV) followed the patients over an average time of 65 months. In this study, the patients’ needs for medical care and for housing were investigated. Patients who were not in cross-sectional remission at baseline had for all the measured variables a higher consumption than those in remission even if the differences were not significant, except for patients who lived in sheltered housing and who had greater need for medical care.

Taking all these findings together, the result of this thesis shows that the attainment of remission provides practical and qualitative advantages to the patients and to society.

Place, publisher, year, edition, pages
Karlstad: Karlstad University , 2009. , p. 78
Series
Karlstad University Studies, ISSN 1403-8099 ; 2009:17
Keywords [en]
Schizophrenia spectrum syndrome, functional outcome, quality of life, neurocognitive performance and need of care
Keywords [sv]
medicinsk psykologi
National Category
Psychology
Research subject
Psychology
Identifiers
URN: urn:nbn:se:kau:diva-3738ISBN: 978-91-7063-240-2 (print)OAI: oai:DiVA.org:kau-3738DiVA, id: diva2:201265
Public defence
2009-06-05, Sjöströmssalen. 1B 309, Karlstad universitet, Karlstad, 10:00 (English)
Opponent
Supervisors
Available from: 2009-05-25 Created: 2009-03-03 Last updated: 2011-10-25Bibliographically approved
List of papers
1. Remission in prognosis of functional outcome: A new dimension in the treatment of patients with psychotic disorders
Open this publication in new window or tab >>Remission in prognosis of functional outcome: A new dimension in the treatment of patients with psychotic disorders
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2007 (English)In: Schizophrenia Research, ISSN 0920-9964, E-ISSN 1573-2509, Vol. 93, p. 160-168Article in journal (Refereed) Published
Identifiers
urn:nbn:se:kau:diva-4050 (URN)10.1016/j.schres.2007.01.014 (DOI)
Available from: 2009-05-14 Created: 2009-05-14 Last updated: 2017-12-13Bibliographically approved
2. Experience of quality of life and attitude to care and treatment in patients with schizophrenia: Role of cross-sectional remission
Open this publication in new window or tab >>Experience of quality of life and attitude to care and treatment in patients with schizophrenia: Role of cross-sectional remission
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2008 (English)In: International journal of psychiatry in clinical practice (Print), ISSN 1365-1501, E-ISSN 1471-1788, Vol. 12, no 2, p. 1-8Article in journal (Refereed) Published
National Category
Psychology
Research subject
Psychology
Identifiers
urn:nbn:se:kau:diva-4053 (URN)10.1080/13651500701660007 (DOI)
Available from: 2009-05-14 Created: 2009-05-14 Last updated: 2017-12-13Bibliographically approved
3. Remission and cognitive ability in a cohort of patients with schizophrenia
Open this publication in new window or tab >>Remission and cognitive ability in a cohort of patients with schizophrenia
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2006 (English)In: Journal of Psychiatric Research, ISSN 0022-3956, E-ISSN 1879-1379, Vol. 40, p. 738-745Article in journal (Refereed) Published
Research subject
Psychology
Identifiers
urn:nbn:se:kau:diva-4054 (URN)10.1016/j.jpsychires.2006.07.005 (DOI)
Available from: 2009-05-14 Created: 2009-05-14 Last updated: 2017-12-13Bibliographically approved
4. The importance of cross-sectional remission in schizophrenia for long-term outcome: A clinical prospective study
Open this publication in new window or tab >>The importance of cross-sectional remission in schizophrenia for long-term outcome: A clinical prospective study
2009 (English)In: Schizophrenia Research, ISSN 0920-9964, E-ISSN 1573-2509, Vol. 115, no 1, p. 67-73Article in journal (Refereed) Published
National Category
Psychology
Research subject
Psychology
Identifiers
urn:nbn:se:kau:diva-4055 (URN)10.1016/j.schres.2009.07.004 (DOI)
Available from: 2009-05-14 Created: 2009-05-14 Last updated: 2017-12-13Bibliographically approved

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