The purpose of this paper is to provide experimental results demonstrating the potential for cationized dialdehyde cellulose as an additive in papermaking wet-ends. Cationized additives have been produced in a sustainable way by deep eutectic solvents (DESs) and their properties were characterized by particle charge detector and polarized-light optical microscopy. Then, three different amounts of the cationized additive (2%, 5%, and 10%) were added to pulp and hand-sheet properties were studied. In addition, the dewatering resistance of the pulps with additives have been evaluated by Schopper-Riegler (°SR) values, water retention values (WRVs) and vacuum dewatering.