This introductory article to the Special Issue ‘Greek Screen Industries’ of the Journal of Greek Media and Culture offers a critical overview of the recently emerging field of Media Industry Studies and situates existing work on Greek screen industries in its context. It argues that the current fragmentation and lack of dialogue between social sciences and arts and humanities approaches on the topic is particularly marked in the Greek context, a fact that can be explained by institutional and historical reasons. It calls for an expansion of the agendas privileged by political economy approaches to screen media towards the more pluralistic, empirical and culture-orientated perspectives facilitated by Media Industry Studies.