Sustainable Development Goals (SDGs), proposed by the United Nations in 2015, give countries around the world much to work on until 2030. The third SDG – Good health and well-being – surely cannot be pursued in isolation. Far from being a silo, it has strong synergies with other SDGs, notably Gender Equality (SDG 5), No Poverty (SDG 1), Reduced Inequalities (SDG 10) & Clean water and sanitation (SDG 6). Quite counter-intuitively, it has trade-offs with SDG 12 (Responsible Consumption and Production). This is a commentary on these synergies and trade-offs, which looks at Good Health and Well-being as an overarching goal on any government’s agenda, impacting and being impacted, to different degrees, by the other goals.