Associations of prenatal exposure to phthalates and one phthalate substitute with anthropometric measures in early life: Results from the German LIFE Child cohort studyShow others and affiliations
2021 (English)In: Baillière's Best Practice & Research. Clinical Endocrinology & Metabolism, ISSN 1521-690X, E-ISSN 1532-1908, Vol. 35, no 5, article id 101532Article in journal (Refereed) Published
Abstract [en]
Exposure to phthalates is widespread and especially early life stages represent a critical window of exposure. In the present study, we investigated the effect of prenatal exposure to phthalates on birth outcomes and weight development in early life. In 130 mother–child pairs, we estimated the association of concentrations of 13 phthalates in spot-urine samples collected during pregnancy and birth outcomes and weight gain in the first two years of life using robust linear regression. High molecular weight phthalates were inversely associated with birth weight in girls but not in boys. Thus, prenatal exposure to phthalates may affect birth weight in a sex-specific manner.
Place, publisher, year, edition, pages
Bailliere Tindall Ltd , 2021. Vol. 35, no 5, article id 101532
Keywords [en]
birth cohort, birth weight, child, phthalates, prenatal exposure, weight gain, body weight gain, cohort analysis, controlled study, female, human, linear regression analysis, male, molecular weight, pregnancy outcome, review, urine sampling
National Category
Occupational Health and Environmental Health Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Public Health Science
Identifiers
URN: urn:nbn:se:kau:diva-85883DOI: 10.1016/j.beem.2021.101532ISI: 000705235700004Scopus ID: 2-s2.0-85109140237OAI: oai:DiVA.org:kau-85883DiVA, id: diva2:1591794
2021-09-072021-09-072022-02-15Bibliographically approved