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Computational study of the effect of hypoxia on cancer response to radiation treatment
Karlstad University, Faculty of Health, Science and Technology (starting 2013), Department of Mathematics and Computer Science (from 2013).
Karlstad Central Hospital; Örebro University.ORCID iD: 0000-0001-6389-7773
Karlstad University, Faculty of Health, Science and Technology (starting 2013), Department of Mathematics and Computer Science (from 2013).ORCID iD: 0000-0002-1160-0007
2020 (English)In: ROMAI Journal, ISSN 1841-5512, E-ISSN 2065-7714, Vol. 16, no 2, p. 75-86Article in journal (Refereed) Published
Abstract [en]

We perform a computational study of the propagation of the oxygen concentration within a two-dimensional slice of a heterogeneous tumour region where the position and shape of the blood vessels are known. Exploiting the parameters space, we explore which effect is noticeable what concerns the formation of hypoxic zones. We use this information to anticipate a patient-specific radiation treatment with a potentially controlled response of the cancer growth.

Place, publisher, year, edition, pages
The Romanian Society of Applied and Industrial Mathematics , 2020. Vol. 16, no 2, p. 75-86
Keywords [en]
Mathematical modeling of hypoxia, finite element method, cancer response to radiation
National Category
Clinical Medicine
Research subject
Mathematics
Identifiers
URN: urn:nbn:se:kau:diva-85511OAI: oai:DiVA.org:kau-85511DiVA, id: diva2:1581517
Available from: 2021-07-22 Created: 2021-07-22 Last updated: 2021-11-18Bibliographically approved

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Korhonen, TopiMuntean, Adrian

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