Rivers as one of the most important topographic factor have played a strategic role not only on the appearance of cities but they also affect the structure and morphology of cities. In this paper I intend to find out the influence of rivers on the morphology of a cities and discuss that how a city in its physical network interacts with a river flowing inside. My study area is river-cities in Sweden in which they have not received much attention in this issue. To this purpose I use space syntax method integrating with geospatial analysis and extract the properties of physical form of cities in terms of global and local integration value, choice value and so on. Comparing the states of presence and absence of rivers in these cities as well as evaluating the effect of rivers on the morphology of areas located in different banks of rivers are also part of interest in this paper. The primary result shows that although a river is not comparable to a city based on size and the area occupied by, it has a significant effect on the form of a city in both global and local properties. In addition, tracking the pattern of river-cities and their interaction to rivers may lead us to interoperate the physical form of these cities in terms of structured and distributed cities.