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The Neural Correlates of Multisensory Integration in Schizophrenia: A Systematic Review
Karlstad University, Faculty of Arts and Social Sciences (starting 2013), Department of Social and Psychological Studies (from 2013).
Karlstad University, Faculty of Arts and Social Sciences (starting 2013), Department of Social and Psychological Studies (from 2013).
2020 (English)Independent thesis Advanced level (professional degree), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Multisensory integration (MSI) is a necessity when creating a comprehensive perception ofthe outside world, by helping us experience sensory signals from different modalities as oneunified percept. It has repeatedly been shown that individuals with schizophrenia suffer fromimpairments in MSI that could explain typical symptoms like hallucinations and realitydistortion. Shedding further light on the neural correlates behind aberrant multisensoryprocesses in schizophrenia gives a greater understanding of the physiognomy of thispsychiatric disorder. We performed a systematic review of the current research of neuralcorrelates during MSI in individuals with schizophrenia compared to healthy controls. Thereview was written according to the Preferred Reporting Items for Systematic Reviews andMeta-analysis (PRISMA). The literature search was made in several databases. The includedarticles involved investigating MSI in diagnosed schizophrenia patients compared to healthycontrols using brain-imaging. Newcastle-Ottawa quality assessment was used to assess risk ofbias. We identified 317 articles through the search whereof 17 were finally included in thereview. The results indicated that multisensory processes in schizophrenia are associated withaberrant, mainly reduced, neural activity as measured in event-related potentials, oscillations,activity and connectivity. The conclusion is that a fronto-temporal region comprising of thefrontal inferior gyrus, middle temporal gyrus and superior temporal gyrus/sulcus along withthe fusiform gyrus and dorsal visual stream in the occipital-parietal lobe, are possible keyregions concerning these deficits.

Place, publisher, year, edition, pages
2020. , p. 33
Keywords [en]
Schizophrenia, multisensory integration, fMRI, EEG, neural correlates, multimodal
National Category
Psychology
Identifiers
URN: urn:nbn:se:kau:diva-78791OAI: oai:DiVA.org:kau-78791DiVA, id: diva2:1447748
Subject / course
Psychology
Educational program
Master of science in psychology programme
Supervisors
Examiners
Available from: 2020-06-30 Created: 2020-06-26 Last updated: 2020-06-30Bibliographically approved

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CiteExportLink to record
Permanent link

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Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • apa.csl
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf