Sense of self plays an important role in human wellbeing and everyday functioning. The experience of self can be affected through perspective taking exercises, which Virtual Reality-technology (VR) can facilitate. This study assumes a Relational Frame Theory-perspective on sense of self as various types of patterns of relational responding about oneself. The study investigates if a visual representation of oneself in a VR-environment (the VR-intervention) can be used to affect the experience of self, in a non-clinical sample (n = 6). Participants' experiences of the VR-intervention and themselves are also investigated. A Single-Case Experimental Design (SCED) and qualitative interviews were used to answer the research questions. The Implicit Relational Assessment Procedure (the IRAP) was conducted as a repeated measure to assess patterns of relational responding about oneself. The qualitative interviews were analyzed thematically. Participant 4 was only included in the thematic analysis due to failed measurements in the IRAP.           Changes in patterns of relational responding about oneself after the VR-intervention, measured with the IRAP, were detected for three participants. Interpretation of change was difficult for two participants, due to high variability in the IRAP. The VR-intervention was unanimously described as a positive experience, enabling an outside perspective. No systematic connection between the IRAP-data and qualitative findings were detected. The results indicate that VR has potential as a therapeutic tool, that patterns of relational responding seem to fluctuate in the IRAP, and that there is a disparity between descriptions about oneself and patterns of relational responding about oneself.