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Methylphenidate and Reduced Overweight in Children With ADHD
Karlstad Cent Hosp, Karlstad, Sweden.;Queen Silvia Childrens Hosp, Gothenburg, Sweden..
Orebro Univ, Campus USO,Sodra Grev Rosengatan 30, S-70362 Orebro, Sweden..
Karlstad Univ, Karlstad, Sweden..
Karlstad Univ, Karlstad, Sweden.;Univ Gothenburg, Gothenburg, Sweden..
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2020 (English)In: Journal of Attention Disorders, ISSN 1087-0547, E-ISSN 1557-1246, Vol. 24, no 2, p. 246-254Article in journal (Refereed) Published
Abstract [en]

Objective: The objective of this study was to investigate odds ratios of overweight/obesity in children with ADHD and to compare the change in body mass index (BMI) after initiation of methylphenidate treatment in normal versus overweight/obese children. Method: This population-based study included 724 children (<18 years), of whom 197 were girls. Odds ratios for overweight and obesity were calculated, comparing the study group with a reference group from the same area. After initiation of methylphenidate treatment, changes in BMI were assessed for up to 3 years. Results: Children with ADHD had an odds ratio of 1.87 (95% confidence interval [CI]: [1.60, 2.19]) for overweight/obesity. A decrease in BMI standard deviation score was identified 1 to 3 years into treatment. The decrease was beneficially greater in overweight/obese as compared with normal weight children-mean (SD) -0.64 (0.80) versus -0.39 (0.68); p = .001-and greater in girls. Conclusion: Medication with methylphenidate may facilitate favorable weight development in children with ADHD and overweight/obesity.

Place, publisher, year, edition, pages
SAGE PUBLICATIONS INC , 2020. Vol. 24, no 2, p. 246-254
Keywords [en]
children, pharmacological treatment, ADHD, weight
Identifiers
URN: urn:nbn:se:kau:diva-76244DOI: 10.1177/1087054718808045ISI: 000504933400007PubMedID: 30371133OAI: oai:DiVA.org:kau-76244DiVA, id: diva2:1388005
Available from: 2020-01-23 Created: 2020-01-23 Last updated: 2020-01-23

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