Epigenetics has revolutionized biological theory since it explains how our life style, including factors such as exercise, stress and nutrition, influences our genes. Epigenetics is the understanding of how the environment interplays with genes, and thus how the environment can affect human characteristics and behaviour. Hence, everyday lifestyle decisions can materialistically explain cell changes and give information about the future health of, for example, students. However, epigenetics is not yet included in the biology curricula in Sweden or many other countries. Therefore, this study aims through a Delphi-study to identify what should be considered as epigenetic literacy and therefore be taught in school. In the Delphi-study a panel of experts related to different fields of epigenetics answers questions about what a citizen needs to know about epigenetics. In the Delphi study we identified three main areas of epigenetic literacy regarding: 1) Epigenetic content knowledge, including core ideas of mechanisms, chromatin, cell differentiation, cell memory, enzymatic control, life history, reversibility and risk. 2) Epigenetic and society, including core ideas of epigenetics related to its influence on lifestyle, diseases, pregnancy, ethics, manipulation of organisms, policy, forensics, policy and crimes. 3) Organization of teaching epigenetics, an area in which most experts recommend that epigenetics should mainly be integrated with the genetic units, but also with other biology topics such as evolution, ecology and health education. Moreover, the Delphi study show that epigenetics is considered a controversial topic from a scientific perspective because the view of epigenetics as a paradigm shift or not differs among the experts. Therefore, many experts recommended that epigenetics should be taught from a nature of science perspective.