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Exfoliated malignant cells in glove and instrument washings following head and neck surgery
Professorial Department of Otolaryngology, Head & Neck Surgery, Dublin, Ireland.
Professorial Department of Otolaryngology, Head & Neck Surgery, Dublin, Ireland.
St. James's Hospital Dublin, Ireland.ORCID iD: 0000-0003-3211-6529
St. James's Hospital Dublin, Ireland.
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1996 (English)In: Clinical Otolaryngology, ISSN 1749-4478, E-ISSN 1365-2273, Vol. 21, no 3, p. 281-283Article in journal (Refereed) Published
Abstract [en]

Loco-regional recurrence following resection of squamous cell carcinoma of the upper aero-digestive tract is a major problem. Cells exfoliated from malignant tumours have been considered capable of implanting and giving rise to local recurrence or metastatic deposits. A prospective study was performed examining washings from the gloves and instruments used in major head and neck operations to determine if exfoliated cells were indeed present. Following removal of the main tumour specimen all surgeons washed their hands in a solution containing a cell fixative and all instruments were soaked in the solution. Samples were then centrifuged and stained using a modified PAP technique. On occasions nuclear fragments consistent with squamous cell carcinoma were present in both glove and instrument washings. We recommend that all surgeons change gloves and instruments following removal of the main tumour specimen and prior to irrigation of the operative field with a tumoricidal agent.

Place, publisher, year, edition, pages
John Wiley & Sons, 1996. Vol. 21, no 3, p. 281-283
National Category
Medical Engineering
Research subject
Information Systems
Identifiers
URN: urn:nbn:se:kau:diva-56992DOI: 10.1111/j.1365-2273.1996.tb01742.xISI: A1996UV49600020PubMedID: 8818504OAI: oai:DiVA.org:kau-56992DiVA, id: diva2:1119886
Available from: 2017-07-05 Created: 2017-07-05 Last updated: 2017-10-11Bibliographically approved

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