The aim of the study was to examine whether there was any difference in the styles of humor affiliative, self-enhancing, aggressive and self-defeating in terms of self-esteem or life satisfaction, and in attitudes to humor depending on self-esteem or life satisfaction. The method was quantitative, and a survey was conducted containing scales with good validity for measuring sense of humor, self-esteem and life satisfaction. 198 respondents participated in the study, a majority of which was found to be women (80%). Data analysis was conducted by an independent two-way analysis of variance (ANOVA 2 * 3), and a correlation analysis. The results showed that there was a significant difference in the affiliative humor style in terms of self-esteem but no difference in terms of self-esteem was found in the other humor styles. No differences were found in any of the humor styles in terms of life satisfaction. The result showed that there was also a difference in sense of humor in terms of self-esteem and that there was a difference in the degree to which one considered himself  as a humorous person in respect of self-esteem. However, there was not any difference on sense of humor in terms of life satisfaction. The correlation analysis showed several significant results, where the affiliative and self-enhancing humor styles were strongly correlated with self-esteem and the self-defeating humor style correlated negatively with self-esteem. However, no correlation with the aggressive humor style was to be found. The study contributed to a better understanding regarding the relationship between humor and self-esteem.