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BETA
von Kobyletzki, Laura B.ORCID iD iconorcid.org/0000-0002-3094-9685
Alternative names
Publications (10 of 19) Show all publications
Beckman, L., Janson, S. & von Kobyletzki, L. B. (2018). Corrigendum to “Associations between neurodevelopmental disorders and factors related to school, health, and social interaction in schoolchildren Results from a Swedish population-based survey” [Disabil Health J 9(4) (2016) 663–672](S1936657416300723)(10.1016/j.dhjo.2016.05.002). Disability and Health Journal, 11(2)
Open this publication in new window or tab >>Corrigendum to “Associations between neurodevelopmental disorders and factors related to school, health, and social interaction in schoolchildren Results from a Swedish population-based survey” [Disabil Health J 9(4) (2016) 663–672](S1936657416300723)(10.1016/j.dhjo.2016.05.002)
2018 (English)In: Disability and Health Journal, ISSN 1936-6574, E-ISSN 1876-7583, Vol. 11, no 2Article in journal (Refereed) Published
Abstract [en]

In the article ‘‘Associations between neurodevelopmental disorders and factors related to school, health, and social interaction in schoolchildren: Results from a Swedish population-based survey’’ Disability and Health Journal 2016; 9(4):663–672 by Linda Beckman, Staffan Janson, and Laura von Kobyletzki on page 2 the ethical considerations under section “Questionnaires, interviews, and health examinations”, the following sentence “The ELSA project has been approved by the regional ethical research committee in Uppsala, Sweden (reg. no: 2013/160).”should read as “The study has been reviewed by the local ethical research committee in Karlstad, Sweden (reg. no: C2015/65).”

Place, publisher, year, edition, pages
Elsevier Inc., 2018
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:kau:diva-66941 (URN)10.1016/j.dhjo.2017.11.003 (DOI)2-s2.0-85044145605 (Scopus ID)
Available from: 2018-04-06 Created: 2018-04-06 Last updated: 2018-04-26Bibliographically approved
Holzgraefe, B., Larsson, A. & von Kobyletzki, L. B. (2018). Do we have scientific evidence about the effect of hypoxaemia on cognitive outcome in adult patients with severe acute respiratory failure?. Upsala Journal of Medical Sciences, 123(1), 68-70
Open this publication in new window or tab >>Do we have scientific evidence about the effect of hypoxaemia on cognitive outcome in adult patients with severe acute respiratory failure?
2018 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 123, no 1, p. 68-70Article in journal (Refereed) Published
Place, publisher, year, edition, pages
Uppsala: Uppsala universitet, 2018
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:kau:diva-67076 (URN)10.1080/03009734.2018.1433255 (DOI)000428060300009 ()29485932 (PubMedID)
Funder
Swedish Research Council, K2015-99X-22731-01-4
Available from: 2018-04-19 Created: 2018-04-19 Last updated: 2018-04-26Bibliographically approved
Chalmers, J. R., Thomas, K. S., Apfelbacher, C., Williams, H. C., Prinsen, C. A., Spuls, P. I., . . . Zaniboni, M. (2018). Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative). British Journal of Dermatology, 178(5), E332-E341
Open this publication in new window or tab >>Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative)
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2018 (English)In: British Journal of Dermatology, ISSN 0007-0963, E-ISSN 1365-2133, Vol. 178, no 5, p. E332-E341Article in journal (Refereed) Published
Abstract [en]

This is the report from the fifth meeting of the Harmonising Outcome Measures for Eczema initiative (HOME V). The meeting was held on 12-14 June 2017 in Nantes, France, with 81 participants. The main aims of the meeting were (i) to achieve consensus over the definition of the core domain of long-term control and how to measure it and (ii) to prioritize future areas of research for the measurement of the core domain of quality of life (QoL) in children. Moderated whole-group and small-group consensus discussions were informed by presentations of qualitative studies, systematic reviews and validation studies. Small-group allocations were performed a priori to ensure that each group included different stakeholders from a variety of geographical regions. Anonymous whole-group voting was carried out using handheld electronic voting pads according to pre-defined consensus rules. It was agreed by consensus that the long-term control domain should include signs, symptoms, quality of life and a patient global instrument. The group agreed that itch intensity should be measured when assessing long-term control of eczema in addition to the frequency of itch captured by the symptoms domain. There was no recommendation of an instrument for the core outcome domain of quality of life in children, but existing instruments were assessed for face validity and feasibility, and future work that will facilitate the recommendation of an instrument was agreed upon.

Place, publisher, year, edition, pages
John Wiley & Sons, 2018
National Category
Dermatology and Venereal Diseases Health Care Service and Management, Health Policy and Services and Health Economy
Identifiers
urn:nbn:se:kau:diva-67487 (URN)10.1111/bjd.16543 (DOI)000432553500006 ()29672835 (PubMedID)
Available from: 2018-06-07 Created: 2018-06-07 Last updated: 2018-07-13Bibliographically approved
von Kobyletzki, L. B., Beckman, L., Smeeth, L., McKee, M., Quint, J. K., Abuabara, K. & Langan, S. (2017). Association between childhood allergic diseases, educational attainment and occupational status in later life: systematic review protocol. BMJ Open, 7(10), Article ID e017245.
Open this publication in new window or tab >>Association between childhood allergic diseases, educational attainment and occupational status in later life: systematic review protocol
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2017 (English)In: BMJ Open, ISSN 2044-6055, E-ISSN 2044-6055, Vol. 7, no 10, article id e017245Article in journal (Refereed) Published
Abstract [en]

Introduction Childhood allergic diseases may prevent affected children from achieving their academic potential. Potential mechanisms include absence from school due to illness and medical appointments. Experience of symptoms in classes or leisure time, and stigma associated with visible signs and symptoms, including skin disease, requirements for medication during school time or the need for specific diets, may also contribute to reduced educational attainment. Studies have investigated the association between specific allergic diseases and educational attainment. The aim of this study is to systematically review the literature on allergic diseases, educational attainment and occupational status, and if possible, calculate meta-analytic summary estimates for the associations. Methods Systematic electronic searches in Medline, EMBASE, Cochrane, Cumulative Index to Nursing & Allied Health Literature (CINAHL), PsycINFO and education Resources Information Center (ERIC); hand search in reference lists of included papers and conference reports; search for unpublished studies in clinical trial registers and the New York Academy of Medicine Grey Literature Report; data extraction; and study quality assessment (Newcastle-Ottawa Scale) will be performed. Analysis Data will be summarised descriptively, and meta-analysis including meta-regression to explore sources of heterogeneities will be performed if possible. Ethics and dissemination Dissemination in a peer-reviewed, open-access, international scientific journal is planned.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2017
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-66055 (URN)10.1136/bmjopen-2017-017245 (DOI)000422617500140 ()
Available from: 2018-02-01 Created: 2018-02-01 Last updated: 2018-05-24Bibliographically approved
Beckman, L., von Kobyletzki, L. B. & Svensson, M. (2017). Determinants of Antidepressants Use and Economic Costs: A Population Based Study. Paper presented at Thirteenth Workshop on Costs and Assessment in Psychiatry "Mental Health Policy and Economics Research: Improving Access, Quality and Outcomes", Venice March 24-26, 2017. Journal of Mental Health Policy and Economics, 20(Suppl.1), S2-S2
Open this publication in new window or tab >>Determinants of Antidepressants Use and Economic Costs: A Population Based Study
2017 (English)In: Journal of Mental Health Policy and Economics, Vol. 20, no Suppl.1, p. S2-S2Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
International Center of Mental Health Policy and Economics, 2017
National Category
Psychiatry
Identifiers
urn:nbn:se:kau:diva-65525 (URN)000400956000004 ()
Conference
Thirteenth Workshop on Costs and Assessment in Psychiatry "Mental Health Policy and Economics Research: Improving Access, Quality and Outcomes", Venice March 24-26, 2017
Available from: 2018-01-04 Created: 2018-01-04 Last updated: 2018-06-27Bibliographically approved
von Kobyletzki, L. B., Thomas, K. S., Schmitt, J., Chalmers, J. R., Deckert, S., Aoki, V., . . . Svensson, A. (2017). What Factors are Important to Patients when Assessing Treatment Response: An International Cross-sectional Survey. Acta Dermato-Venereologica, 97(1), 86-90
Open this publication in new window or tab >>What Factors are Important to Patients when Assessing Treatment Response: An International Cross-sectional Survey
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2017 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 97, no 1, p. 86-90Article in journal (Refereed) Published
Abstract [en]

This study investigated the perspective of international patients on individual symptoms of atopic dermatitis (eczema) in determining treatment response. A questionnaire was developed to evaluate the importance of symptoms from the patient's perspective. Patients were asked: "How important are these features in deciding whether or not a treatment is working?", and rated symptoms on a 5-point Likert scale. Patients were approached via Harmonising Outcome Measures for Eczema (HOME) collaborators and self-selected to take part in the on-line survey. Patients from 34 countries (n = 1,111) completed the survey; of these, 423 (38.3%) were parents of children with eczema. Ten items were rated as being "quite important" or "very important" by more than 80% of the respondents: itch, pain/soreness, skin feels hot or inflamed, bleeding, involvement of visible or sensitive body sites, cracks, sleep difficulties, amount of body affected, and weeping/oozing. These results may be of use in determining the face validity of scales from a cross-cultural patients' perspective.

Place, publisher, year, edition, pages
Acta dermato-venereologica, 2017
Keywords
eczema, dermatitis, atopic, outcome assessment
National Category
Nursing
Identifiers
urn:nbn:se:kau:diva-64723 (URN)10.2340/00015555-2480 (DOI)000393894700017 ()27305646 (PubMedID)
Available from: 2017-10-19 Created: 2017-10-19 Last updated: 2018-06-27Bibliographically approved
Chalmers, J. R., Simpson, E., Apfelbacher, C. J., Thomas, K. S., von Kobyletzki, L. B., Schmitt, J., . . . Spuls, P. I. (2016). Report from the fourth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative). British Journal of Dermatology, 175(1), 69-79
Open this publication in new window or tab >>Report from the fourth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative)
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2016 (English)In: British Journal of Dermatology, ISSN 0007-0963, E-ISSN 1365-2133, Vol. 175, no 1, p. 69-79Article in journal (Refereed) Published
Abstract [en]

This article is a report of the fourth meeting of the Harmonising Outcome Measures for Eczema (HOME) initiative held in Malmo, Sweden on 23-24 April 2015 (HOME IV). The aim of the meeting was to achieve consensus over the preferred outcome instruments for measuring patient-reported symptoms and quality of life for the HOME core outcome set for atopic eczema (AE). Following presentations, which included data from systematic reviews, consensus discussions were held in a mixture of whole group and small group discussions. Small groups were allocated a priori to ensure representation of different stakeholders and countries. Decisions were voted on using electronic keypads. For the patient-reported symptoms, the group agreed by vote that itch, sleep loss, dryness, redness/inflamed skin and irritated skin were all considered essential aspects of AE symptoms. Many instruments for capturing patient-reported symptoms were discussed [ including the Patient-Oriented SCOring Atopic Dermatitis index, Patient-Oriented Eczema Measure (POEM), Self-Administered Eczema Area and Severity Index, Itch Severity Scale, Atopic Dermatitis Quickscore and the Nottingham Eczema Severity Score] and, by consensus, POEM was selected as the preferred instrument to measure patient-reported symptoms. Further work is needed to determine the reliability and measurement error of POEM. Further work is also required to establish the importance of pain/soreness and the importance of collecting information regarding the intensity of symptoms in addition to their frequency. Much of the discussion on quality of life concerned the Dermatology Life Quality Index and Quality of Life Index for Atopic Dermatitis; however, consensus on a preferred instrument for measuring this domain could not be reached. In summary, POEM is recommended as the HOME core outcome instrument for measuring AE symptoms.

National Category
Public Health, Global Health, Social Medicine and Epidemiology Dermatology and Venereal Diseases
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-47007 (URN)10.1111/bjd.14773 (DOI)000380917600017 ()27436240 (PubMedID)
Available from: 2016-11-02 Created: 2016-11-02 Last updated: 2018-07-20Bibliographically approved
von Kobyletzki, L. B., Thomas, K., Schmitt, J., Chalmers, J., Deckert, S., Aoki, V. & Svensson, A. (2014). Eczema signs and symptoms: what is important to patients?. Paper presented at 8th Georg Rajka Symposium on Atopic Dermatitis (ISAD), MAY 21-23, 2014, Nottingham, ENGLAND. British Journal of Dermatology, 170(6), E11-E11
Open this publication in new window or tab >>Eczema signs and symptoms: what is important to patients?
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2014 (English)In: British Journal of Dermatology, ISSN 0007-0963, E-ISSN 1365-2133, Vol. 170, no 6, p. E11-E11Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
Wiley-Blackwell Publishing Inc., 2014
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-41522 (URN)000337952200023 ()
Conference
8th Georg Rajka Symposium on Atopic Dermatitis (ISAD), MAY 21-23, 2014, Nottingham, ENGLAND
Available from: 2016-04-25 Created: 2016-04-11 Last updated: 2017-11-30Bibliographically approved
von Kobyletzki, L. B., Bornehag, C.-G., Breeze, E., Larsson, M., Lindström Boman, C. & Svensson, A. (2014). Factors Associated with Remission of Eczema in Children: A Population-based Follow-up Study. Acta Dermato-Venereologica, 90(2), 179-184
Open this publication in new window or tab >>Factors Associated with Remission of Eczema in Children: A Population-based Follow-up Study
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2014 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 90, no 2, p. 179-184Article in journal (Refereed) Published
Abstract [en]

The aim of this study was to analyse factors associated with remission of atopic dermatitis (AD) in childhood. A population-based AD cohort of 894 children aged 1-3 years from a cross-sectional baseline study in 2000 was followed up in 2005. The association between remission, background, health, lifestyle, and environmental variables was estimated with crude and multivariable logistic regression. At follow-up, 52% of the children had remission. Independent factors at baseline predicting remission were: milder eczema (adjusted odds ratio (aOR), 1.43; 95% confidence interval (95% CI) 1.16-1.77); later onset of eczema (aOR 1.40; 95% CI 1.08-1.80); non-flexural eczema (aOR 2.57; 95% CI 1.62-4.09); no food allergy (aOR 1.51; 95% CI 1.11-2.04), and rural living (aOR 1.48; 95% CI 1.07-2.05). Certain aspects of AD and rural living were important for remission, but despite the initial hypotheses to the contrary, the environmental factors examined in this paper were not substantial predictors of remission.

Keywords
eczema, atopic dermatitis, children
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-30113 (URN)10.2340/00015555-1681 (DOI)000332820000010 ()24037118 (PubMedID)
Available from: 2013-11-22 Created: 2013-11-22 Last updated: 2017-12-06Bibliographically approved
Schmitt, J., Langan, S., Deckert, S., Svensson, A., von Kobyletzki, L. B., Thomas, K. S. & Spuls, P. (2014). How to measure clinical signs of atopic dermatitis?: A systematic review and recommendation. Paper presented at 8th Georg Rajka Symposium on Atopic Dermatitis (ISAD), MAY 21-23, 2014, Nottingham, ENGLAND. British Journal of Dermatology, 170(6), E40-E41
Open this publication in new window or tab >>How to measure clinical signs of atopic dermatitis?: A systematic review and recommendation
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2014 (English)In: British Journal of Dermatology, ISSN 0007-0963, E-ISSN 1365-2133, Vol. 170, no 6, p. E40-E41Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
Wiley-Blackwell Publishing Inc., 2014
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-41520 (URN)000337952200090 ()
Conference
8th Georg Rajka Symposium on Atopic Dermatitis (ISAD), MAY 21-23, 2014, Nottingham, ENGLAND
Available from: 2016-04-25 Created: 2016-04-11 Last updated: 2017-11-30Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-3094-9685

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