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Bornehag, Carl-GustafORCID iD iconorcid.org/0000-0003-0417-1686
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Publications (10 of 161) Show all publications
Zhao, Y., Wang, J., Liu, G., Ataei, Y., Bornehag, C.-G., Liu, W., . . . Sun, Y. (2024). The CHECH study: A prospective pregnancy cohort study on CHemical exposure and children’s health in Tianjin, China. Hygiene and Environmental Health Advances, 9, Article ID 100084.
Open this publication in new window or tab >>The CHECH study: A prospective pregnancy cohort study on CHemical exposure and children’s health in Tianjin, China
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2024 (English)In: Hygiene and Environmental Health Advances, ISSN 2773-0492, Vol. 9, article id 100084Article in journal (Refereed) Published
Abstract [en]

The CHemical Exposure and Children’s Health (CHECH) study is an ongoing pregnancy cohort study in Tianjin, China. This paper describes the background, aim and the study design, which can be followed by future researchers to design and conduct similar studies. The abundance and the potential adverse health outcomes of endocrine disrupting chemicals (EDCs) is concerning. More notably, developing fetuses and infants are more vulnerable to EDCs exposure. The CHECH study aims to investigate the importance of early life exposure to multiple EDCs (phthalates and their metabolites, bisphenol A and their substitutes, perfluorinated compounds and poly brominated diphenyl ethers) for multiple health outcomes in Chinese children, namely sexual development, neurodevelopment, metabolism and growth, as well as asthma and allergy. A total of 2238 pregnant women were recruited in Tianjin from May 2017 to April 2021 with a response rate of 90 %. Among these women, 2255 children were born with available information, including 47 pairs of twins. Urine samples were collected from pregnant women and children, while air and dust samples were obtained from the home environment during pregnancy and infancy periods. Information on children’s health was gathered through physical examinations and questionnaires. The CHECH study, which collected exposure information and health outcomes at multiple time points, will contribute to the understanding of prenatal exposure to EDCs and their impact on children’s health, thereby facilitating the development of risk assessments aimed at reducing exposure and associated health risks. 

Place, publisher, year, edition, pages
Elsevier, 2024
Keywords
Birth cohort study, Endocrine disruptors, Health, Infant, Methodology
National Category
Occupational Health and Environmental Health
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-97901 (URN)10.1016/j.heha.2023.100084 (DOI)2-s2.0-85179488862 (Scopus ID)
Available from: 2024-01-03 Created: 2024-01-03 Last updated: 2024-01-03Bibliographically approved
Di Criscio, M., Lodahl, J. E., Stamatakis, A., Kitraki, E., Bakoyiannis, I., Repouskou, A., . . . Rüegg, J. (2023). A human-relevant mixture of endocrine disrupting chemicals induces changes in hippocampal DNA methylation correlating with hyperactive behavior in male mice. Chemosphere, 313, Article ID 137633.
Open this publication in new window or tab >>A human-relevant mixture of endocrine disrupting chemicals induces changes in hippocampal DNA methylation correlating with hyperactive behavior in male mice
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2023 (English)In: Chemosphere, ISSN 0045-6535, E-ISSN 1879-1298, Vol. 313, article id 137633Article in journal (Refereed) Published
Abstract [en]

Humans are ubiquitously exposed to endocrine disrupting chemicals (EDCs), substances that interfere with endogenous hormonal signaling. Exposure during early development is of particular concern due to the programming role of hormones during this period. A previous epidemiological study has shown association between prenatal co-exposure to 8 EDCs (Mixture N1) and language delay in children, suggesting an effect of this mixture on neurodevelopment. Furthermore, in utero exposure to Mixture N1 altered gene expression and behavior in adult mice. In this study, we investigated whether epigenetic mechanisms could underlie the long term effects of Mixture N1 on gene expression and behavior. To this end, we analyzed DNA methylation at regulatory regions of genes whose expression was affected by Mixture N1 in the hippocampus of in utero exposed mice using bisulfite-pyrosequencing. We show that Mixture N1 decreases DNA methylation in males at three genes that are part of the hypothalamus-pituitary-adrenal (HPA) axis: Nr3c1, Nr3c2, and Crhr1, coding for the glucocorticoid receptor, the mineralocorticoid receptor, and the corticotropin releasing hormone receptor 1, respectively. Furthermore, we show that the decrease in Nr3c1 methylation correlates with increased gene expression, and that Nr3c1, Nr3c2, and Crhr1 methylation correlates with hyperactivity and reduction in social behavior. These findings indicate that an EDC mixture corresponding to a human exposure scenario induces epigenetic changes, and thus programming effects, on the HPA axis that are reflected in the behavioral phenotypes of the adult male offspring. 

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Alkylation, Behavioral research, Brain, DNA, Endocrine disrupters, Gene expression, Hormones, Mammals, Chemical mixtures, DNA Methylation, Endocrine disrupting chemicals, Exposed to, Genes expression, Hippocampus, Human relevant mixture, Hyperactive behavior, Hypothalamus-pituitary-adrenal axis, Male mouse, Methylation, adult, DNA, endocrine disruptor, gene expression, hormone, male, methylation
National Category
Pharmacology and Toxicology Endocrinology and Diabetes
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-92928 (URN)10.1016/j.chemosphere.2022.137633 (DOI)000913946900001 ()36565761 (PubMedID)2-s2.0-85144941074 (Scopus ID)
Funder
EU, Horizon 2020, 634880, 825759
Available from: 2023-01-13 Created: 2023-01-13 Last updated: 2023-02-23Bibliographically approved
Marinopoulou, M., Billstedt, E., Wessman, C., Bornehag, C.-G. & Unenge Hallerbäck, M. (2023). Association Between Intellectual Functioning and Autistic Traits in the General Population of Children. Child Psychiatry and Human Development
Open this publication in new window or tab >>Association Between Intellectual Functioning and Autistic Traits in the General Population of Children
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2023 (English)In: Child Psychiatry and Human Development, ISSN 0009-398X, E-ISSN 1573-3327Article in journal (Refereed) Epub ahead of print
Abstract [en]

Autistic traits are continuously distributed in the general population. The associations between autistic traits and intellectual functioning and/or behavioural difficulties, and the impact of intellectual functioning on behavioural difficulties are unclear. The study aims to describe the distribution of autistic traits in a population-based cross-sectional sample of children. Further aims are to examine the association between intellectual functioning and autistic traits, and between autistic traits and behavioural difficulties. Wechsler scales and ratings of autistic traits and behavioural problems in 874 children aged 7-9 years in the Swedish Environmental Longitudinal Mother and Child, Asthma and Allergy (SELMA) study were assessed. We found a continuous distribution of autistic traits. Intellectual functioning was negatively associated with autistic traits but not with behavioural difficulties. Behavioural difficulties were associated with autistic traits.

Place, publisher, year, edition, pages
Springer, 2023
Keywords
Intellectual functioning, Autistic traits, Behavioural problems, Wechsler scales
National Category
Psychiatry
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-96024 (URN)10.1007/s10578-023-01562-5 (DOI)001011965100001 ()37351708 (PubMedID)2-s2.0-85162685213 (Scopus ID)
Funder
Region Värmland, [LIVFOU-938951EU, Horizon 2020, 634880
Available from: 2023-07-06 Created: 2023-07-06 Last updated: 2023-07-07Bibliographically approved
Derakhshan, A., Shu, H., Broeren, M. A. .., Kortenkamp, A., Lindh, C. H., Demeneix, B., . . . Korevaar, T. I. .. (2023). Association of endocrine disrupting chemicals exposure with human chorionic gonadotropin concentrations in pregnancy. Environment International, 178, Article ID 108091.
Open this publication in new window or tab >>Association of endocrine disrupting chemicals exposure with human chorionic gonadotropin concentrations in pregnancy
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2023 (English)In: Environment International, ISSN 0160-4120, E-ISSN 1873-6750, Vol. 178, article id 108091Article in journal (Refereed) Published
Abstract [en]

Background: Human chorionic gonadotropin (hCG) is produced by the placenta and plays an essential role in the maintenance of pregnancy. Endocrine disrupting chemicals (EDCs) have the potential to interfere with functions related to the production and secretion of hCG; however associations between exposure to EDCs and hCG concentrations in humans remain to be elucidated. Objectives: To investigate the association of urinary, serum and plasma concentrations of EDCs during pregnancy with serum hCG concentrations. Methods: We utilized data form the Swedish Environmental Longitudinal, Mother and child, Asthma and allergy (SELMA) study. We investigated the association of 26 EDCs measured in early pregnancy urine or blood with serum hCG concentrations using multi-variable adjusted linear regression models per EDC and Weighted Quantile Sum (WQS) regression with repeated holdout validation for the EDCs mixture. Results: In 2,039 included women, higher exposure to bisphenol A was associated with lower hCG (beta [95% CI]: −0.06 [−0.11 to −0.002]) while higher triclosan exposure was associated with a higher hCG (0.02 [0.003 to 0.04]). Higher exposure to several phthalates, including mono-ethyl and mono-butyl phthalates (MEP and MBP) as well as metabolites of di-2-ethylhexyl phthalate (DEHP) was associated with a lower hCG (beta [95% CI] for sum of DEHP metabolites: −0.13 [−0.19 to −0.07]). Likewise, higher exposure to several polychlorinated biphenyls (PCBs) was associated with a lower hCG. In the WQS regression, each quartile increase in the EDCs mixture was associated with −0.27 lower hCG (95% CI: −0.34 to −0.19). Discussion: Higher exposure to several EDCs during pregnancy was associated with a lower hCG; and despite the small effect sizes, still indicating that the exposure may negatively affect production or secretion of hCG by the placenta. Our results provide the impetus for future experimental studies to investigate the placenta as a target organ for adverse effects of EDCs. 

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Endocrine disrupters, Esters, Obstetrics, Organic pollutants, Polychlorinated biphenyls, Regression analysis, Chemical exposure, Chemical mixtures, Di(2-ethylhexyl)phthalate, Endocrine disrupting chemicals, High exposures, Human chorionic gonadotrophins, Human remains, Phthalates, Placenta, Pregnancy, concentration (composition), endocrine disruptor, hormone, metabolite, PCB, plasma, pregnancy, serum, urine, Metabolites
National Category
Obstetrics, Gynecology and Reproductive Medicine Occupational Health and Environmental Health
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-96296 (URN)10.1016/j.envint.2023.108091 (DOI)001039358800001 ()37459690 (PubMedID)2-s2.0-85165125139 (Scopus ID)
Funder
Lund UniversityEU, Horizon 2020, 825161Swedish Research Council FormasRegion Skåne
Available from: 2023-08-09 Created: 2023-08-09 Last updated: 2023-08-17Bibliographically approved
Sapounidou, M., Andersson, P. L., Leemans, M., Fini, J.-B., Demeneix, B., Rüegg, J., . . . Gennings, C. (2023). From Cohort to Cohort: A Similar Mixture Approach (SMACH) to Evaluate Exposures to a Mixture Leading to Thyroid-Mediated Neurodevelopmental Effects Using NHANES Data. Toxics, 11(4), Article ID 331.
Open this publication in new window or tab >>From Cohort to Cohort: A Similar Mixture Approach (SMACH) to Evaluate Exposures to a Mixture Leading to Thyroid-Mediated Neurodevelopmental Effects Using NHANES Data
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2023 (English)In: Toxics, E-ISSN 2305-6304, Vol. 11, no 4, article id 331Article in journal (Refereed) Published
Abstract [en]

Prenatal exposure to a mixture (MIX N) of eight endocrine-disrupting chemicals has been associated with language delay in children in a Swedish pregnancy cohort. A novel approach was proposed linking this epidemiological association with experimental evidence, where the effect of MIX N on thyroid hormone signaling was assessed using the Xenopus eleuthero-embryonic thyroid assay (XETA OECD TG248). From this experimental data, a point of departure (PoD) was derived based on OECD guidance. Our aim in the current study was to use updated toxicokinetic models to compare exposures of women of reproductive age in the US population to MIX N using a Similar Mixture Approach (SMACH). Based on our findings, 66% of women of reproductive age in the US (roughly 38 million women) had exposures sufficiently similar to MIX N. For this subset, a Similar Mixture Risk Index (SMRIHI) was calculated comparing their exposures to the PoD. Women with SMRIHI > 1 represent 1.1 million women of reproductive age. Older women, Mexican American and other/multi race women were less likely to have high SMRIHI values compared to Non-Hispanic White women. These findings indicate that a reference mixture of chemicals identified in a Swedish cohort—and tested in an experimental model for establishment of (PoDs)—is also of health relevance in a US population. 

Place, publisher, year, edition, pages
MDPI, 2023
Keywords
causal inference, endocrine-disrupting chemicals, mixtures risk assessment
National Category
Occupational Health and Environmental Health Obstetrics, Gynecology and Reproductive Medicine Pharmacology and Toxicology
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-94660 (URN)10.3390/toxics11040331 (DOI)000979631100001 ()37112558 (PubMedID)2-s2.0-85153771851 (Scopus ID)
Funder
EU, Horizon 2020, 234880
Available from: 2023-05-15 Created: 2023-05-15 Last updated: 2023-05-26Bibliographically approved
Marinopoulou, M., Unenge Hallerbäck, M., Bornehag, C.-G. & Billstedt, E. (2023). Is WISC-IV Working Memory Index associated with ADHD symptoms in 7-8-year-olds?. Applied neuropsychology. Child
Open this publication in new window or tab >>Is WISC-IV Working Memory Index associated with ADHD symptoms in 7-8-year-olds?
2023 (English)In: Applied neuropsychology. Child, ISSN 2162-2965Article in journal (Refereed) Epub ahead of print
Abstract [en]

The Working Memory Index (WMI) in the Wechsler Intelligence Scale for Children (WISC) has been suggested to be associated with ADHD symptoms. The relationship between WMI and ADHD symptoms in the general population is not clear. The study aimed to examine the association between working memory (WM) and behavioral regulation (BR), and hyperactivity/inattention (HI) in a general population sample of 7-8-year-olds, and whether general intellectual functioning is associated with BR and HI. The study also examined if those with low WMI also fulfill elevated ADHD criteria. The study group (N = 865) was assessed with the WISC (Fourth edition), the Behavior Rating Inventory of Executive Function, the Strengths and Difficulties Questionnaire, and the Five to Fifteen Questionnaire, and divided into three groups based on WM function, and in relation to BR and/or HI problems. The associations between WM and BR, and WM and HI, including intellectual functioning as covariate, were examined. WM deficits were found in 22%, but the majority of those had no BR or HI problems. Four percent in the study group had WM deficits combined with BR and/or HI problems, and in about one third of those inattentive ADHD criteria were fulfilled. WM and prosocial behavior were associated with BR and HI. WM deficits measured with WISC WMI in 7-8-year-olds do not always signal BR and/or HI problems.

Place, publisher, year, edition, pages
Taylor & Francis, 2023
Keywords
Community sample, hyperactivity, inattention, WISC-IV, working memory
National Category
Psychiatry
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-93897 (URN)10.1080/21622965.2023.2176232 (DOI)000934457200001 ()36780371 (PubMedID)2-s2.0-85148298527 (Scopus ID)
Funder
EU, Horizon 2020, 634880Region Värmland, LIVFOU-938951; LIVFOU-967660AnnMari och Per Ahlqvists Stiftelse, 20191206
Available from: 2023-03-09 Created: 2023-03-09 Last updated: 2023-08-17Bibliographically approved
Svensson, K., Gennings, C., Hagenäs, L., Wolk, A., Håkansson, N., Wikström, S. & Bornehag, C.-G. (2023). Maternal nutrition during mid-pregnancy and children’s body composition at seven years of age in the SELMA study. British Journal of Nutrition, 130(11), 1982-1992
Open this publication in new window or tab >>Maternal nutrition during mid-pregnancy and children’s body composition at seven years of age in the SELMA study
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2023 (English)In: British Journal of Nutrition, ISSN 0007-1145, E-ISSN 1475-2662, Vol. 130, no 11, p. 1982-1992Article in journal (Refereed) Published
Abstract [en]

Optimal nutrition during pregnancy is vital for both maternal and child health. Our objective was to explore if prenatal diet is associated with children’s height and body fat. Nutrient intake was assessed through a food-frequency questionnaire from 808 pregnant women and summarized to a nutrition index, "My Nutrition Index"(MNI). The association with children’s height and body fat (bioimpedance) was assessed with linear regression models. Secondary analysis was performed with BMI, trunk fat and skinfolds. Overall, higher MNI score was associated with greater height (β=0.47; (95% CI: 0.00, 0.94), among both sexes. Among boys, higher MNI was associated with 0.15 higher BMI z-scores, 0.12 body fat z-scores, 0.11 trunk fat z-scores, and larger triceps, and triceps + subscapular skinfolds (β=0.05 and β=0.06; on the log2 scale) (p-value<0.05). Among girls, the opposite associations were found with 0.12 lower trunk fat z-scores, and smaller subscapular and suprailiac skinfolds (β= -0.07 and β= -0.10; on the log2 scale) (p-value<0.05). For skinfold measures this would represent a ±1.0 millimeters difference. Unexpectedly, a prenatal diet in line with recommended nutrient intake was associated with higher measures of body fat for boys and opposite to girls at a pre-pubertal stage of development. 

Place, publisher, year, edition, pages
Cambridge University Press, 2023
Keywords
adult, article, body composition, body fat, body mass, child, female, food frequency questionnaire, human, linear regression analysis, major clinical study, maternal nutrition, nutrient intake, pregnancy, pregnant woman, school child, secondary analysis, skinfold, triceps brachii muscle, trunk
National Category
Pediatrics Nutrition and Dietetics
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-95208 (URN)10.1017/S0007114523000983 (DOI)001007759800001 ()37232113 (PubMedID)2-s2.0-85160806932 (Scopus ID)
Available from: 2023-06-12 Created: 2023-06-12 Last updated: 2023-12-11Bibliographically approved
Özel, F., Stratmann, M., Lindh, C., Gennings, C., Bornehag, C.-G. & Rüegg, J. (2023). Prenatal exposure to phthalates and gender-specific play behavior at seven years of age in the SELMA study. Environment International, 178, Article ID 108029.
Open this publication in new window or tab >>Prenatal exposure to phthalates and gender-specific play behavior at seven years of age in the SELMA study
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2023 (English)In: Environment International, ISSN 0160-4120, E-ISSN 1873-6750, Vol. 178, article id 108029Article in journal (Refereed) Published
Abstract [en]

Background: A growing body of evidence shows that prenatal exposure to phthalates affects child development. Since many phthalates have been shown to alter endocrine signaling, they may influence reproductive development, neurodevelopment, and child behavior. Indeed, a few studies reported associations between prenatal phthalate exposure and gender-specific play behavior. However, evidence for this relationship is limited, and previous findings are based on single phthalates, while human exposure entails mixtures of chemicals. Objective: We aimed to investigate the associations between prenatal exposure to single phthalates, as well as a phthalate mixture, and gender-specific play behavior. Methods: A total of 715 mother–child pairs from the Swedish Environmental Longitudinal, Mother and Child, Asthma and Allergy (SELMA) study were included. In the median week 10 of pregnancy, phthalate metabolites were measured in urine. Gender-specific play behavior was measured with Preschool Activities Inventory at the age of seven years. Linear and weighted quantile sum regressions were used; data was stratified by sex. Models were adjusted for child and maternal age, maternal education, parental attitudes toward play behavior, and urinary creatinine concentration. Results: For boys, single compound analyses revealed negative associations of prenatal exposure to di-isononyl phthalate (DINP) concentrations with masculine (β = −1.44; 95% CI = −2.72, −0.16) and composite (β = −1.43; 95% CI = −2.72, −0.13) scores. Suggestive associations were also observed with a mixture approach identifying DINP as the main contributor of the association of decreased masculine play. Among girls, higher urinary concentrations of 2,4-methyl-7-oxyooctyl-oxycarbonyl-cyclohexane carboxylic acid (MOiNCH) was associated with decreased feminine (β = −1.59; 95% CI = −2.62, −0.57) and masculine scores (β = −1.22; 95% CI = −2.14, −0.29), whereas the mixture analyses did not yield conclusive results for girls. Conclusion: Our findings suggest associations of prenatal exposure to DINP with decreased masculine play behavior in boys while the results for girls were not fully conclusive.

Place, publisher, year, edition, pages
Elsevier, 2023
National Category
Occupational Health and Environmental Health Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-95938 (URN)10.1016/j.envint.2023.108029 (DOI)001028013400001 ()37331180 (PubMedID)2-s2.0-85162084243 (Scopus ID)
Funder
Region VärmlandSwedish Asthma and Allergy AssociationEU, Horizon 2020Swedish Research Council FormasVårdal FoundationSwedish Research Council
Available from: 2023-07-04 Created: 2023-07-04 Last updated: 2023-08-08Bibliographically approved
Svensson, K., Gennings, C., Lindh, C., Kiviranta, H., Rantakokko, P., Wikström, S. & Bornehag, C.-G. (2023). Prenatal exposures to mixtures of endocrine disrupting chemicals and sex-specific associations with children’s BMI and overweight at 5.5 years of age in the SELMA study. Environment International, 179, Article ID 108176.
Open this publication in new window or tab >>Prenatal exposures to mixtures of endocrine disrupting chemicals and sex-specific associations with children’s BMI and overweight at 5.5 years of age in the SELMA study
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2023 (English)In: Environment International, ISSN 0160-4120, E-ISSN 1873-6750, Vol. 179, article id 108176Article in journal (Refereed) Published
Abstract [en]

Background: Prenatal exposure to mixtures of endocrine disrupting chemicals (EDC) has the potential to disrupt human metabolism. Prenatal periods are especially sensitive as many developmental processes are regulated by hormones. Prenatal exposure to EDCs has inconsistently been associated with children’s body mass index (BMI) and obesity. The objective of this study was to investigate if prenatal exposure to a mixture of EDCs was associated with children’s BMI and overweight (ISO-BMI ≥ 25) at 5.5 years of age, and if there were sex-specific effects. Methods: A total of 1,105 mother–child pairs with complete data on prenatal EDCs concentrations (e.g., phthalates, non-phthalate plasticizers, phenols, PAH, pesticides, PFAS, organochlorine pesticides, and PCBs), children’s measured height and weight, and selected covariates in the Swedish Environmental Longitudinal, Mother and child, Asthma and allergy (SELMA) study were included in this analysis. The mixture effect of EDCs with children’s BMI and overweight was assessed using WQS regression with 100 repeated holdouts. A positively associated WQS index with higher BMI and odds of overweight was derived. Models with interaction term and stratified weights by sex was applied in order to evaluate sex-specific associations. Results: A significant WQS*sex interaction term was identified and associations for boys and girls were in opposite directions. Higher prenatal exposure to a mixture of EDCs was associated with lower BMI (Mean β = -0.19, 95%CI: −0.40, 0.01) and lower odds of overweight (Mean OR = 0.72, 95%CI: 0.48, 1.04) among girls with borderline significance. However, the association among boys did not reach statistical significance. Among girls, the possible chemicals of concern were MEP, 2-OHPH, BPF, BPS, DPP and PFNA. Conclusion: Prenatal exposure to a mixture of EDCs was associated with lower BMI and overweight among girls, and non-significant associations among boys. Chemicals of concern for girls included phthalates, non-phthalate plasticizers, bisphenols, PAHs, and PFAS.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Association reactions, Endocrine disrupters, Phenols, Plasticizers, Polychlorinated biphenyls, Polycyclic aromatic hydrocarbons, Solvents, Body mass, Body mass index, Child, Endocrine disrupting chemicals, Mass index, Overweight, Pregnancy, Prenatal exposure
National Category
Occupational Health and Environmental Health Public Health, Global Health, Social Medicine and Epidemiology Pediatrics
Research subject
Public Health Science
Identifiers
urn:nbn:se:kau:diva-96758 (URN)10.1016/j.envint.2023.108176 (DOI)001078491500001 ()37672941 (PubMedID)2-s2.0-85169918152 (Scopus ID)
Funder
Landstinget i Värmland
Available from: 2023-09-19 Created: 2023-09-19 Last updated: 2023-11-02Bibliographically approved
Lichtensteiger, W., Bassetti-Gaille, C., Rehrauer, H., Felix Escalera, J., Linillos-Pradillo, B., Idrissi, H., . . . Schlumpf, M. (2023). Transcriptomics in Developing Rat Hippocampus Perinatally Exposed to Environmental Endocrine Active Chemicals and Impaired Memory Function in Adult Offspring: Convergence of Chemical Actions on Common Signalling Pathways. In: : . Paper presented at 57th Congress of the European-Societies-of-Toxicology (EUROTOX),Ljubljana, Slovenia, September10-13, 2023. (pp. S129-S129). Elsevier, 384
Open this publication in new window or tab >>Transcriptomics in Developing Rat Hippocampus Perinatally Exposed to Environmental Endocrine Active Chemicals and Impaired Memory Function in Adult Offspring: Convergence of Chemical Actions on Common Signalling Pathways
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2023 (English)Conference paper, Poster (with or without abstract) (Other academic)
Place, publisher, year, edition, pages
Elsevier, 2023
National Category
Pharmacology and Toxicology Environmental Sciences
Research subject
History; Public Health Science
Identifiers
urn:nbn:se:kau:diva-97385 (URN)10.1016/S0378-4274(23)00568-4 (DOI)001065901700305 ()
Conference
57th Congress of the European-Societies-of-Toxicology (EUROTOX),Ljubljana, Slovenia, September10-13, 2023.
Funder
EU, Horizon 2020, 825759
Available from: 2023-11-16 Created: 2023-11-16 Last updated: 2023-11-16Bibliographically approved
Projects
An in vitro pipeline for investigating species differences in developmental neurotoxicity [2021-01090_VR]; Uppsala University
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0003-0417-1686

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